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SARS-CoV-2 对叙利亚仓鼠中流感病毒复制的干扰。

SARS-CoV-2 Interference of Influenza Virus Replication in Syrian Hamsters.

机构信息

Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.

出版信息

J Infect Dis. 2022 Jan 18;225(2):282-286. doi: 10.1093/infdis/jiab587.

DOI:10.1093/infdis/jiab587
PMID:34875072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8689717/
Abstract

In hamsters, SARS-CoV-2 infection at the same time as or before H3N2 influenza virus infection resulted in significantly reduced influenza virus titers in the lungs and nasal turbinates. This interference may be correlated with SARS-CoV-2-induced expression of MX1.

摘要

在仓鼠中,SARS-CoV-2 感染与 H3N2 流感病毒感染同时或之前发生,导致肺部和鼻甲骨中的流感病毒滴度显著降低。这种干扰可能与 SARS-CoV-2 诱导的 MX1 表达有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be4/8763958/cc697cd0a286/jiab587f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be4/8763958/3e2ab57d8443/jiab587f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be4/8763958/cc697cd0a286/jiab587f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be4/8763958/3e2ab57d8443/jiab587f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be4/8763958/cc697cd0a286/jiab587f0002.jpg

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