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2019冠状病毒病与慢性疲劳综合征:内分泌学视角

COVID-19 and chronic fatigue syndrome: An endocrine perspective.

作者信息

Bansal Rashika, Gubbi Sriram, Koch Christian A

机构信息

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.

Department of Medicine, Fox Chase Cancer Center, Philadelphia, PA, United States.

出版信息

J Clin Transl Endocrinol. 2022 Mar;27:100284. doi: 10.1016/j.jcte.2021.100284. Epub 2021 Dec 3.

DOI:10.1016/j.jcte.2021.100284
PMID:34877261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8641402/
Abstract

Patients recovering from COVID-19 may have persistent debilitating symptoms requiring long term support through individually tailored cardiopulmonary and psychological rehabilitation programs. Clinicians need to be aware about the likely long-term complications and their diagnostic assessments to help identify any occult problems requiring additional help. Endocrinological evaluations should be considered as part of the armamentarium in the management of such individuals with diligent cognizance about the involvement of the hypothalamo-pituitary-adrenal (HPA) axis, adrenal and thyroid function. We here review the literature and potential pathophysiological mechanisms involved in and related to post COVID-19 symptoms with an emphasis on endocrine function.

摘要

新冠病毒感染康复患者可能会出现持续的衰弱症状,需要通过个性化的心肺和心理康复计划获得长期支持。临床医生需要了解可能出现的长期并发症及其诊断评估方法,以帮助识别任何需要额外帮助的隐匿问题。在内分泌评估时,应充分认识下丘脑 - 垂体 - 肾上腺(HPA)轴、肾上腺和甲状腺功能的受累情况,将其作为此类患者管理手段的一部分。我们在此回顾与新冠病毒感染后症状相关的文献及潜在病理生理机制,重点关注内分泌功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8500/8739452/33206e830ffd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8500/8739452/03d2373b0ce2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8500/8739452/33206e830ffd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8500/8739452/03d2373b0ce2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8500/8739452/33206e830ffd/gr2.jpg

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本文引用的文献

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Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: Systematic review and meta-analysis.评估无症状新冠病毒感染的程度及其社区传播潜力:系统评价与荟萃分析。
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Climate Change and Obesity.气候变化与肥胖
Horm Metab Res. 2021 Sep;53(9):575-587. doi: 10.1055/a-1533-2861. Epub 2021 Sep 8.
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Hashimoto's thyroiditis following SARS-CoV-2 infection.感染 SARS-CoV-2 后发生桥本甲状腺炎。
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Front Cell Neurosci. 2024 Dec 18;18:1481963. doi: 10.3389/fncel.2024.1481963. eCollection 2024.
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Int J Mol Sci. 2024 Nov 2;25(21):11791. doi: 10.3390/ijms252111791.
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