Liu Guo-Feng, Wang Xiao-Ze, Luo Xue-Feng
Department of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
World J Clin Cases. 2021 Nov 6;9(31):9577-9583. doi: 10.12998/wjcc.v9.i31.9577.
Hepatic encephalopathy (HE) is a frequent and debilitating complication of chronic liver disease. Recurrent HE is strongly linked with spontaneous portosystemic shunts (SPSSs). Intrahepatic arterioportal fistulas (IAPFs) occur rarely but pose a major clinical challenge and may lead to or worsen portal hypertension. Herein, we present a rare case of recurrent HE secondary to a SPSS combined with an IAPF.
A 63-year-old female with primary biliary cirrhosis presented with recurrent disturbance of consciousness for 4 mo. SPSS communicating the superior mesenteric vein with the inferior vena cava and IAPF linking the intrahepatic artery with the portal vein were found on contrast-enhanced abdominal computed tomography. The patient did not respond well to medical treatment. Therefore, simultaneous embolization of SPSS and IAPF was scheduled. After embolization, the symptoms of HE showed obvious resolution.
The presence of liver vascular disorders should not be neglected in patients with chronic liver disease, and interventional therapy is a reasonable choice in such patients.
肝性脑病(HE)是慢性肝病常见且使人衰弱的并发症。复发性HE与自发性门体分流(SPSS)密切相关。肝内动门脉瘘(IAPF)很少见,但构成重大临床挑战,可能导致门静脉高压或使其恶化。在此,我们报告一例罕见的继发于SPSS合并IAPF的复发性HE病例。
一名63岁原发性胆汁性肝硬化女性患者,出现意识障碍反复4个月。腹部增强计算机断层扫描发现肠系膜上静脉与下腔静脉相通的SPSS以及肝内动脉与门静脉相连的IAPF。该患者对药物治疗反应不佳。因此,计划对SPSS和IAPF进行同步栓塞。栓塞后,HE症状明显缓解。
慢性肝病患者不应忽视肝脏血管疾病的存在,介入治疗对此类患者是合理的选择。