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沙尘暴与山谷热(球孢子菌病)之间无一致关联。

No Consistent Link Between Dust Storms and Valley Fever (Coccidioidomycosis).

作者信息

Comrie Andrew C

机构信息

University of Arizona Tucson AZ USA.

出版信息

Geohealth. 2021 Dec 1;5(12):e2021GH000504. doi: 10.1029/2021GH000504. eCollection 2021 Dec.

Abstract

Dust storms, such as those associated with haboobs and strong regional winds, are frequently assumed to cause increases in cases of Valley fever (coccidioidomycosis). The disease is caused by inhaling arthroconidia of fungi that, after being disturbed from semi-desert subsoil, have become airborne. Fungal arthroconidia can be transported in low-wind conditions as well as in individual dust events, but there is no reliable evidence that all or most dust storms consistently lead to subsequent increases in coccidioidomycosis cases. Following a review of the relevant literature, this study examines the relationship between dust storms and coccidioidomycosis cases to determine if there is a consistent and general association between them. All recorded dust storms from 2006 to 2020 in and near the Phoenix area of Maricopa County, Arizona and the Bakersfield area of Kern County, California were used in a compositing analysis (superposed epoch analysis) of subsequent coccidioidomycosis cases in each area. Analyses of monthly and weekly disease case data showed no statistical differences in the patterns of coccidioidomycosis cases following dust storms versus non-dust storm conditions, for the entire data set as well as for seasonal subsets of the data. This study thoroughly analyzes post-dust storm coccidioidomycosis cases for a large set of dust storms, and it confirms and expands upon previous literature, including a recent study that measured airborne arthroconidia and found no consistent links connecting wind and dust conditions to increases in coccidioidomycosis.

摘要

沙尘暴,比如与哈布沙暴和强烈区域风相关的沙尘暴,常常被认为会导致山谷热(球孢子菌病)病例增加。这种疾病是由于吸入真菌的关节孢子所致,这些真菌在被从半荒漠下层土壤扰动后,进入了空气中。真菌关节孢子在低风速条件下以及在个别沙尘事件中都可能传播,但没有可靠证据表明所有或大多数沙尘暴都会持续导致随后球孢子菌病病例增加。在对相关文献进行综述之后,本研究考察了沙尘暴与球孢子菌病病例之间的关系,以确定它们之间是否存在一致且普遍的关联。利用亚利桑那州马里科帕县凤凰城地区及周边以及加利福尼亚州克恩县贝克斯菲尔德地区2006年至2020年期间所有记录的沙尘暴,对每个地区随后的球孢子菌病病例进行了合成分析(叠加时代分析)。对月度和每周疾病病例数据的分析表明,对于整个数据集以及数据的季节性子集,沙尘暴后与非沙尘暴情况下球孢子菌病病例模式没有统计学差异。本研究对大量沙尘暴后的球孢子菌病病例进行了全面分析,证实并扩展了先前的文献,包括最近一项测量空气中关节孢子的研究,该研究发现风和沙尘条件与球孢子菌病增加之间没有一致的联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f4/8628988/cf7a97482785/GH2-5-e2021GH000504-g002.jpg

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