Dermatology and Venereology Unit, Department of Medicine Solna, Karolinska Institutet, SE-171 76 Stockholm, Sweden.
Acta Derm Venereol. 2022 Jan 4;102:adv00624. doi: 10.2340/actadv.v101.737.
Swedish databases present unique opportunities to research population data on diseases and treatments. The current study is, to our knowledge, the most comprehensive registry-based study on a chronic urticaria population in Sweden to date. The aim of this study was to describe the chronic urticaria population in Stockholm County regarding epidemiology, demographics, comorbidity, healthcare usage and treatment patterns in relation to current international guidelines. Real-world data were extracted between 2013 and 2019, yielding 10,642 adult patients. Study period prevalence of chronic urticaria was 0.53%, the mean annual incidence was approximately 0.08%, and 68% of patients were female. Regarding diagnosis, 58% were first diagnosed in primary care, approximately 50% were diagnosed before the age of 40 years. Regarding type of urticaria, 89% had chronic spontaneous urticaria, 11% had chronic inducible urticaria, and 5% of patients with chronic urticaria had coexisting angioedema. Common coexisting diagnoses were, for example, asthma, allergy, psychiatric and behavioural disorders and cardiometabolic disorders. Treatment patterns generally followed guidelines, yet data indicated that guidelines were not fully implemented, especially in primary care.
瑞典数据库为研究疾病和治疗的人群数据提供了独特的机会。据我们所知，目前这项研究是迄今为止针对瑞典慢性荨麻疹人群进行的最全面的基于登记的研究。本研究的目的是描述斯德哥尔摩郡的慢性荨麻疹人群，包括流行病学、人口统计学、合并症、医疗保健使用情况和与当前国际指南相关的治疗模式。在 2013 年至 2019 年期间提取了真实世界的数据，共纳入了 10642 名成年患者。研究期间慢性荨麻疹的患病率为 0.53%，年平均发病率约为 0.08%，68%的患者为女性。在诊断方面，58%的患者在初级保健中首次被诊断，约 50%的患者在 40 岁之前被诊断。在荨麻疹类型方面，89%为慢性自发性荨麻疹，11%为慢性诱导性荨麻疹，5%的慢性荨麻疹患者伴有血管性水肿。常见的合并诊断包括哮喘、过敏、精神和行为障碍以及心血管代谢疾病等。治疗模式总体上遵循指南，但数据表明指南并未得到完全实施，尤其是在初级保健中。
