Doueihy Celina, Chelala Dania, Ossaili Hadi, Hachem Gebrael El, Zeidan Sandy, Ghoul Balsam El, Aoun Mabel
Saint-Joseph University of Beirut (Dr Doueihy, Dr Chelala, Dr Ossaili, Dr Hachem, Dr Aoun), Hotel-Dieu de France Hospital (Dr Chelala), Beirut; Centre Hospitalier du Nord, Mazraat Jnaid (Dr Zeidan, Dr Ghoul); Saint-George Hospital Ajaltoun, Ajaltoun (Dr Aoun), Lebanon.
J Occup Environ Med. 2022 Mar 1;64(3):e103-e108. doi: 10.1097/JOM.0000000000002458.
More patients are reaching end-stage kidney disease without evident cause. This study aims to explore occupational risk factors associated with hemodialysis.
A multicenter matched case-control study included dialysis patients and age, sex, and diabetes-matched controls (normal kidney function). Conditional logistic regression analysis assessed occupational factors associated with dialysis.
Two hundred thirty eight hemodialysis patients and 238 controls were included. History of occupational heat exposure (odds ratio [OR] = 1.93; 95% confidence interval [CI]: 1.24 to 3.00), working as a cook (OR = 12; 95% CI: 1.56 to 92.29), as construction worker (OR = 10; 95% CI: 1.28 to 78.12) were associated with higher risk of dialysis. These results were significant in men and in those with kidney disease of unknown etiology.
Occupational heat exposure was found to be associated with hemodialysis. This is an important step for future development of preventive strategies in high-risk professions.
越来越多的患者在没有明显病因的情况下发展到终末期肾病。本研究旨在探讨与血液透析相关的职业危险因素。
一项多中心匹配病例对照研究纳入了透析患者以及年龄、性别和糖尿病相匹配的对照组（肾功能正常）。条件逻辑回归分析评估了与透析相关的职业因素。
共纳入238例血液透析患者和238例对照。职业热暴露史（比值比[OR]=1.93；95%置信区间[CI]：1.24至3.00）、厨师职业（OR=12；95%CI：1.56至92.29）、建筑工人职业（OR=10；95%CI：1.28至78.12）与更高的透析风险相关。这些结果在男性和病因不明的肾病患者中具有显著性。
发现职业热暴露与血液透析相关。这是高危职业未来制定预防策略的重要一步。
