Tariq Madiha, Zahid Muhammad Abdullah, Khan Taimoor Ashraf, Shah Hira Ghafar
Unit 1, Institute of Ophthalmology, Mayo Hospital, Lahore, Pakistan.
Department of Medicine, Army Medical College, Rawalpindi, Pakistan.
Oman J Ophthalmol. 2021 Oct 20;14(3):184-186. doi: 10.4103/ojo.ojo_64_21. eCollection 2021 Sep-Dec.
Ligneous conjunctivitis is a rare disease in which pseudomembranes develop on the mucosal surfaces of the eye. Only a handful of cases have been reported in the past 100 years. Although plasminogen deficiency is largely implicated in the pathogenesis of this condition, infectious agents are also thought to play a role in worsening the disease. Treatment is usually challenging. We present a case of 3-year-old female in whom a multidrug-resistant was isolated from the culture of the pseudomembranes. To the best of our knowledge, this is the first time has been implicated as an exacerbation factor. Furthermore, we have given merit to the triple regimen of corticosteroids, heparin, and cyclosporine as being effective. We also added antibiotics to target the infectious organism.
木质化结膜炎是一种罕见疾病，眼部黏膜表面会形成假膜。在过去100年里仅报道过少数病例。虽然纤溶酶原缺乏在该病发病机制中起主要作用，但感染因素也被认为会使病情恶化。治疗通常具有挑战性。我们报告一例3岁女性病例，从其假膜培养物中分离出一种多重耐药菌。据我们所知，这是首次将该菌作为病情加重因素。此外，我们认为皮质类固醇、肝素和环孢素三联疗法有效。我们还添加了抗生素来针对感染病原体。
