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温肾调经汤对多囊卵巢综合征月经失调患者激素水平及卵泡数量的影响

Effect of Wenshentiaojing Decoction on Hormone Level and Follicular Number in Patients with Menstrual Disorder of Polycystic Ovary Syndrome.

作者信息

Li Lanzhi, Huang Ning, Qi Yanyan, Li Yan, Wang Lu

机构信息

Department of Physical Examination, Yantaishan Hospital, Yantai 264000, China.

Renal Interventional Department, Affiliated Qingdao Central Hospital, Qingdao University, Qingdao 266000, China.

出版信息

Evid Based Complement Alternat Med. 2021 Nov 29;2021:4975867. doi: 10.1155/2021/4975867. eCollection 2021.

DOI:10.1155/2021/4975867
PMID:34880919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8648443/
Abstract

OBJECTIVE

To explore the curative effect of Wenshentiaojing Decoction on the treatment of menstrual disorder caused by PCOS.

METHODS

Patients with menstrual disorders caused by PCOS admitted to our department from January 2020 to January 2021 were selected as the research objects and were divided into a control group and observation group according to the random number table method. The control group was treated with Western medicine, and the observation group was treated with Wenshentiaojing Decoction on the basis of Western medicine. The clinical efficacy of the two groups was compared. Before and after treatment, sex hormones (LH, FSH, LH/FSH, and testosterone (T)), ovarian volume, endometrial thickness, cervical mucus score, follicular number, menstrual conditions (menstrual duration, menstrual cycle, and menstrual volume), and other indicators in both groups were recorded.

RESULTS

After treatment, the total effective rate of the observation group (91.1% (41/45)) was higher than that of the control group (77.8% (35/45)), and the difference was statistically significant ( < 0.05). After treatment, the LH, LH/FSH, and T levels in the observation group were lower than those in the control group, while the FSH level was higher than that in the control group ( < 0.05). After treatment, the ovarian volume, endometrial thickness, cervical mucus score, and follicle number in the observation group were higher than those in the control group ( < 0.05). After treatment, the menstrual duration and menstrual volume in the observation group were longer than those in the conventional group, and the menstrual cycle was shorter than that in the conventional group ( < 0.05).

CONCLUSION

For patients with menstrual disorders caused by PCOS, the treatment effect of Wenshentiaojing Decoction assisted with Western medicine is better, which can effectively improve the level of sex hormones, cervical mucus, and menstrual conditions, increase the ovarian volume, endometrial thickness, and follicle number, and improve the treatment effect, with fewer adverse reactions, which is worthy of further promotion and application.

摘要

目的

探讨温肾调经汤治疗多囊卵巢综合征所致月经失调的疗效。

方法

选取2020年1月至2021年1月我院收治的多囊卵巢综合征所致月经失调患者作为研究对象,采用随机数字表法分为对照组和观察组。对照组采用西药治疗,观察组在西药治疗基础上加用温肾调经汤。比较两组的临床疗效。记录两组治疗前后的性激素(LH、FSH、LH/FSH及睾酮(T))、卵巢体积、子宫内膜厚度、宫颈黏液评分、卵泡数目、月经情况(经期、月经周期及月经量)等指标。

结果

治疗后,观察组总有效率为91.1%(41/45),高于对照组的77.8%(35/45),差异有统计学意义(<0.05)。治疗后,观察组LH、LH/FSH及T水平低于对照组,FSH水平高于对照组(<0.05)。治疗后,观察组卵巢体积、子宫内膜厚度、宫颈黏液评分及卵泡数目高于对照组(<0.05)。治疗后,观察组经期及月经量长于传统组,月经周期短于传统组(<0.05)。

结论

对于多囊卵巢综合征所致月经失调患者,温肾调经汤辅助西药治疗效果更佳,可有效改善性激素水平、宫颈黏液及月经情况,增加卵巢体积、子宫内膜厚度及卵泡数目,提高治疗效果,不良反应较少,值得进一步推广应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/28c5c75e217a/ECAM2021-4975867.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/b4d541dc0168/ECAM2021-4975867.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/35e048684247/ECAM2021-4975867.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/6b20be91f651/ECAM2021-4975867.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/7f65a9eff79c/ECAM2021-4975867.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/a48679e79681/ECAM2021-4975867.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/28c5c75e217a/ECAM2021-4975867.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/b4d541dc0168/ECAM2021-4975867.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/35e048684247/ECAM2021-4975867.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/6b20be91f651/ECAM2021-4975867.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/7f65a9eff79c/ECAM2021-4975867.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/a48679e79681/ECAM2021-4975867.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/8648443/28c5c75e217a/ECAM2021-4975867.006.jpg

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