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妊娠相关不适当窦性心动过速:母婴结局的队列分析

Pregnancy-related inappropriate sinus tachycardia: A cohort analysis of maternal and fetal outcomes.

作者信息

Sharp Alexander, Patient Charlotte, Pickett Janet, Belham Mark

机构信息

Department of Cardiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Department of Obstetrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

出版信息

Obstet Med. 2021 Dec;14(4):230-234. doi: 10.1177/1753495X21990196. Epub 2021 Mar 16.

DOI:10.1177/1753495X21990196
PMID:34880936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8646219/
Abstract

BACKGROUND

Little literature exists regarding the syndrome of inappropriate sinus tachycardia during pregnancy. We aimed to further understand the natural history of inappropriate sinus tachycardia in pregnancy, and to explore maternal and fetal outcomes.

METHODS

A retrospective, observational cohort analysis of 19 pregnant women who presented with inappropriate sinus tachycardia.

RESULTS

42% attended the emergency department on more than one occasion with symptoms of inappropriate sinus tachycardia; 32% required hospital admission and 26% required pharmacological therapy. There were no maternal deaths, instances of heart failure or acute coronary syndrome, and no thromboembolic or haemorrhagic complications during pregnancy. Rates of caesarean section were similar to the background rate of our unit (32% and 27%, respectively). Rates of induction were notably elevated (58% vs 25%).

CONCLUSION

Inappropriate sinus tachycardia in pregnancy is associated with high rates of hospitalization and induction of labour, which may not be mandatory given the clinical findings in this group of women.

摘要

背景

关于妊娠期不适当窦性心动过速综合征的文献较少。我们旨在进一步了解妊娠期不适当窦性心动过速的自然病史,并探讨母婴结局。

方法

对19例出现不适当窦性心动过速的孕妇进行回顾性观察队列分析。

结果

42%的患者因不适当窦性心动过速症状多次前往急诊科就诊;32%的患者需要住院治疗,26%的患者需要药物治疗。孕期无孕产妇死亡、心力衰竭或急性冠状动脉综合征病例,也无血栓栓塞或出血并发症。剖宫产率与我们科室的基线率相似(分别为32%和27%)。引产率显著升高(58%对25%)。

结论

妊娠期不适当窦性心动过速与高住院率和引产率相关,鉴于该组女性的临床发现,这些可能并非必要。

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本文引用的文献

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Gestation-Specific Vital Sign Reference Ranges in Pregnancy.妊娠特异性生命体征参考范围。
Obstet Gynecol. 2020 Mar;135(3):653-664. doi: 10.1097/AOG.0000000000003721.
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Trends of blood pressure and heart rate in normal pregnancies: a systematic review and meta-analysis.正常妊娠血压和心率变化趋势:系统评价和荟萃分析。
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Inappropriate sinus tachycardia in pregnancy: a benign phenomena?妊娠期不适当窦性心动过速:一种良性现象?
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2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope.2015年心律协会关于体位性心动过速综合征、不适当窦性心动过速和血管迷走性晕厥诊断与治疗的专家共识声明
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A longitudinal study of maternal cardiovascular function from preconception to the postpartum period.一项从孕前到产后阶段对孕产妇心血管功能的纵向研究。
J Hypertens. 2014 Apr;32(4):849-56. doi: 10.1097/HJH.0000000000000090.
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