Mahmoud Yehia A-G, El-Naggar Mehrez E, Abdel-Megeed Ahmed, El-Newehy Mohamed
Department of Botany and Microbiology, Faculty of Science, Tanta University, Tanta 31527, Egypt.
Textile Research Division, National Research Center (Affiliation ID: 60014618), Cairo 12622, Egypt.
Polymers (Basel). 2021 Nov 26;13(23):4136. doi: 10.3390/polym13234136.
Polysaccharide materials are widely applied in different applications including food, food packaging, drug delivery, tissue engineering, wound dressing, wastewater treatment, and bioremediation sectors. They were used in these domains due to their efficient, cost-effective, non-toxicity, biocompatibility, and biodegradability. As is known, polysaccharides can be synthesized by different simple, facile, and effective methods. Of these polysaccharides are cellulose, Arabic gum, sodium alginate, chitosan, chitin, curdlan, dextran, pectin, xanthan, pullulan, and so on. In this current article review, we focused on discussing the synthesis and potential applications of microbial polysaccharides. The biosynthesis of polysaccharides from microbial sources has been considered. Moreover, the utilization of molecular biology tools to modify the structure of polysaccharides has been covered. Such polysaccharides provide potential characteristics to transfer toxic compounds and decrease their resilience to the soil. Genetically modified microorganisms not only improve yield of polysaccharides, but also allow economically efficient production. With the rapid advancement of science and medicine, biosynthesis of polysaccharides research has become increasingly important. Synthetic biology approaches can play a critical role in developing polysaccharides in simple and facile ways. In addition, potential applications of microbial polysaccharides in different fields with a particular focus on food applications have been assessed.
多糖材料广泛应用于不同领域,包括食品、食品包装、药物递送、组织工程、伤口敷料、废水处理和生物修复等领域。由于其高效、成本效益高、无毒、生物相容性好和可生物降解性,它们被用于这些领域。众所周知,多糖可以通过不同简单、便捷且有效的方法合成。这些多糖包括纤维素、阿拉伯胶、海藻酸钠、壳聚糖、几丁质、凝胶多糖、葡聚糖、果胶、黄原胶、普鲁兰多糖等等。在本文综述中,我们重点讨论了微生物多糖的合成及其潜在应用。我们考虑了从微生物来源生物合成多糖的方法。此外,还涵盖了利用分子生物学工具修饰多糖结构的内容。这类多糖具有转移有毒化合物并降低其在土壤中持久性的潜在特性。转基因微生物不仅提高了多糖产量,还实现了经济高效的生产。随着科学和医学的快速发展,多糖生物合成研究变得越来越重要。合成生物学方法可以在以简单便捷的方式开发多糖方面发挥关键作用。此外,还评估了微生物多糖在不同领域的潜在应用,尤其侧重于食品应用。