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结冷胶作为一种独特的微生物多糖:其特性、合成及当前应用趋势

Gellan Gum as a Unique Microbial Polysaccharide: Its Characteristics, Synthesis, and Current Application Trends.

作者信息

Abdl Aali Raghad Abdl Karim, Al-Sahlany Shayma Thyab Gddoa

机构信息

Department of Food Science, College of Agriculture, University of Basrah, Basrah City 61004, Iraq.

出版信息

Gels. 2024 Mar 6;10(3):183. doi: 10.3390/gels10030183.

DOI:10.3390/gels10030183
PMID:38534601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10970089/
Abstract

Gellan gum (GG) is a linear, negatively charged exopolysaccharide that is biodegradable and non-toxic. When metallic ions are present, a hard and transparent gel is produced, which remains stable at a low pH. It exhibits high water solubility, can be easily bio-fabricated, demonstrates excellent film/hydrogel formation, is biodegradable, and shows biocompatibility. These characteristics render GG a suitable option for use in food, biomedical, and cosmetic fields. Thus, this review paper offers a concise summary of microbial polysaccharides. Moreover, an in-depth investigation of trends in different facets of GG, such as biosynthesis, chemical composition, and physical and chemical properties, is emphasized. In addition, this paper highlights the process of extracting and purifying GG. Furthermore, an in-depth discussion of the advantages and disadvantages of GG concerning other polysaccharides is presented. Moreover, the utilization of GG across different industries, such as food, medicine, pharmaceuticals, cosmetics, etc., is thoroughly examined and will greatly benefit individuals involved in this field who are seeking fresh opportunities for innovative projects in the future.

摘要

结冷胶(GG)是一种线性、带负电荷的胞外多糖,具有可生物降解和无毒的特性。当存在金属离子时,会形成坚硬且透明的凝胶,该凝胶在低pH值下仍保持稳定。它具有高水溶性,易于生物制造,展现出优异的成膜/水凝胶性能,可生物降解,并具有生物相容性。这些特性使结冷胶成为食品、生物医学和化妆品领域的合适选择。因此,本文对微生物多糖进行了简要概述。此外,还着重深入研究了结冷胶在不同方面的发展趋势,如生物合成、化学组成以及物理和化学性质。此外,本文还突出了结冷胶的提取和纯化过程。此外,还对结冷胶相对于其他多糖的优缺点进行了深入讨论。此外,还全面考察了结冷胶在食品、医药、制药、化妆品等不同行业的应用,这将极大地造福于该领域中未来寻求创新项目新机遇的相关人员。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73f/10970089/31407584db38/gels-10-00183-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73f/10970089/9e54ac1c4b7d/gels-10-00183-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73f/10970089/31407584db38/gels-10-00183-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73f/10970089/9e54ac1c4b7d/gels-10-00183-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73f/10970089/31407584db38/gels-10-00183-g002.jpg

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Pharmaceutics. 2024 Feb 20;16(3):298. doi: 10.3390/pharmaceutics16030298.
2
Gel properties and interactions of hydrogels constructed with low acyl gellan gum and puerarin.低酰基结冷胶与葛根素构建水凝胶的凝胶性能及相互作用。
Carbohydr Polym. 2024 Feb 15;326:121594. doi: 10.1016/j.carbpol.2023.121594. Epub 2023 Nov 17.
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Synthesis and characterization of gellan gum-based hydrogels for drug delivery applications.
用于生物医学应用(如伤口敷料)的二氧化钛纳米颗粒掺入结冷胶水凝胶的绿色生物合成。
Front Chem. 2025 Apr 17;13:1560213. doi: 10.3389/fchem.2025.1560213. eCollection 2025.
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Microbial-Derived Biopolymers: A Pathway to Sustainable Civil Engineering.微生物衍生生物聚合物:通往可持续土木工程的途径
Polymers (Basel). 2025 Jan 12;17(2):172. doi: 10.3390/polym17020172.
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Advances in Microbial Exopolysaccharides: Present and Future Applications.微生物胞外多糖的研究进展:现状与未来应用。
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