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使用吻合钮进行食管离断术治疗肝硬化食管静脉曲张出血的长期疗效。

Long term results after portal disconnection of the esophagus using an anastomotic button for bleeding esophageal varices in cirrhosis.

作者信息

Prioton J B, Feneyrou B, Michel H, Bories P, Bertrand L, Blanc F

出版信息

Surg Gynecol Obstet. 1986 Aug;163(2):121-6.

PMID:3488593
Abstract

From 1968 to 1984, 250 patients with cirrhosis and bleeding esophageal varices underwent portal disconnection of the esophagus using either Murphy's button (before 1974) or an esophageal device developed by one of the authors (after 1974). One hundred and thirty-four patients underwent operation on an elective basis and 116 underwent emergency procedures. With the use of Child's classification, 62 patients were class A, 125 were class B and 63, class C. The over-all operative mortality rate was 24.4 per cent but this varied with the hepatic functional status and whether or not the operation was done on an elective or emergency basis. The long term survival rates were 53 per cent at one year, 36 per cent at three years, 24 per cent at five years and 8 per cent at ten years. Ninety-six per cent of the patients were without proved recurrent esophageal bleeding at one year, 88 per cent at three years, 79 per cent at five years and 66 per cent at ten years. Portal disconnection of the esophagus using an anastomotic button is a simple and effective procedure which can benefit many patients with cirrhosis who undergo an operation for bleeding varices on an elective or emergency basis. It constitutes an efficacious prophylactic means for preventing recurrent bleeding from esophageal varices.

摘要

1968年至1984年期间,250例肝硬化合并食管静脉曲张破裂出血患者接受了食管断流术,1974年以前使用墨菲氏钮,1974年以后使用作者之一研制的食管装置。134例患者择期手术,116例患者急诊手术。根据Child分级,A级62例,B级125例,C级63例。总体手术死亡率为24.4%,但因肝功能状态以及手术是择期还是急诊而有所不同。1年生存率为53%,3年生存率为36%,5年生存率为24%,10年生存率为8%。96%的患者1年时无证实的食管再出血,3年时为88%,5年时为79%,10年时为66%。使用吻合钮进行食管断流术是一种简单有效的手术方法,可使许多因择期或急诊手术治疗静脉曲张破裂出血的肝硬化患者受益。它是预防食管静脉曲张再出血的一种有效预防手段。

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