Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Consultant Nephrologist, St. George Medical Centre, Kitchener, ON N2R 0H3, Canada.
Int J Environ Res Public Health. 2021 Dec 2;18(23):12710. doi: 10.3390/ijerph182312710.
The aim of this study was to assess the adequacy of dietary folate intake and perceptions of pill burden among Saudi patients on maintenance hemodialysis (MHD). This was a cross-sectional study of adults (>18 years) on MHD (>3 months) attending the dialysis unit at King Saud University Medical City. Patient demographics, dietary folic acid intake, and perceptions of pill burden were collected. Fifty-four patients met the eligibility criteria, with a mean age of 57 ± 15.5 years. The majority were females (63%), and the most prevalent comorbidities were diabetes (43%) and hypertension (76%). The average number of medications/patients was 11 ± 2.9, and most patients were receiving folate supplementation (68.5%). The average dietary folate intake was 823 ± 530 mcg/day. Pill burden was bothersome, primarily due to taking too many medications (57%) while taking medications at the workplace was the least bothersome burden (17%). The reported high pill burden and adequate dietary folate intake by Saudi patients on MHD indicates that the omission of folate supplementation may be advantageous for this special population.
本研究旨在评估沙特维持性血液透析（MHD）患者的膳食叶酸摄入充足程度和对药物负担的认知。这是一项横断面研究，纳入了在沙特国王大学医学城透析中心接受 MHD（>3 个月）治疗的成年（>18 岁）患者。收集了患者的人口统计学特征、叶酸摄入情况和药物负担认知情况。符合条件的 54 名患者的平均年龄为 57 ± 15.5 岁，其中大多数为女性（63%），最常见的合并症是糖尿病（43%）和高血压（76%）。平均每位患者用药 11 ± 2.9 种，大多数患者正在接受叶酸补充（68.5%）。平均膳食叶酸摄入量为 823 ± 530 mcg/天。药物负担较为麻烦，主要是因为服用的药物过多（57%），而在工作场所服用药物的负担最小（17%）。沙特 MHD 患者报告的高药物负担和充足的膳食叶酸摄入表明，对于这一特殊人群来说，可能有利的是不补充叶酸。
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