新型 Δ-四氢大麻酚汽化器含有未经标注的掺杂物、化学合成的非预期副产物和重金属。
Novel Δ-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals.
机构信息
Department of Environmental Medicine, University of Rochester Medical Center, Rochester, New York 14642, United States.
出版信息
Chem Res Toxicol. 2022 Jan 17;35(1):73-76. doi: 10.1021/acs.chemrestox.1c00388. Epub 2021 Dec 10.
Abstract
Cannabis e-cigarettes containing Δ-tetrahydrocannabinol (Δ-THC) produced synthetically from hemp-derived cannabidiol (CBD) have recently risen in popularity as a legal means of cannabis consumption, but questions surrounding purity and unlabeled additives have created doubts of their safety. Herein, NMR, GC-MS, and ICP-MS were used to analyze major components of 27 products from 10 brands, and it was determined none of these had accurate Δ-THC labeling, 11 had unlabeled cutting agents, and all contained reaction side-products including olivetol, Δ--tetrahydrocannabinol, 9-ethoxyhexahydrocannabinol, Δ-tetrahydrocannabinol (Δ-THC), heavy metals, and a novel previously undescribed cannabinoid, -tetrahydrocannabifuran.
摘要
大麻电子烟含有 Δ-四氢大麻酚（Δ-THC），这是一种从大麻衍生的大麻二酚（CBD）中合成的物质，最近作为一种合法的大麻消费方式越来越受欢迎，但有关纯度和未标记添加剂的问题引发了对其安全性的怀疑。在此，使用 NMR、GC-MS 和 ICP-MS 分析了 10 个品牌的 27 种产品的主要成分，结果表明，这些产品均未进行准确的 Δ-THC 标记，有 11 种产品含有未标记的切割剂，并且均含有反应副产物，包括橄榄醇、Δ--四氢大麻酚、9-乙氧基六氢大麻酚、Δ-四氢大麻酚（Δ-THC）、重金属和一种以前未描述过的新型大麻素，-四氢大麻呋喃。
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