Ningbo Institute of Northwestern Polytechnical University, Frontiers Science Center for Flexible Electronics (FSCFE), Shaanxi Institute of Flexible Electronics (SIFE), Shaanxi Institute of Biomedical Materials and Engineering (SIBME), Northwestern Polytechnical University, Xi'an, Shaanxi 710072, People's Republic of China.
Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture, Fisheries College, Jimei University, Xiamen, Fujian 361021, People's Republic of China.
J Agric Food Chem. 2021 Dec 22;69(50):15039-15051. doi: 10.1021/acs.jafc.1c06676. Epub 2021 Dec 10.
In recent years, the deterioration of the aquaculture ecological environment has led to a high incidence of fish diseases. Lysozymes, important antimicrobial enzymes, play an important role in the innate immune system of fish. The studies of fish lysozymes benefit the control of fish infections caused by pathogens. In this review, we reviewed recent progress in fish lysozymes, including their classification, structural characteristics, biological functions and mechanisms, tissue distributions, and properties of their recombinant proteins, which will help us to systematically understand the fish lysozymes and facilitate their applications in the fields of food and agriculture.
近年来,水产养殖生态环境恶化导致鱼类疾病高发。溶菌酶作为重要的抗菌酶,在鱼类先天免疫系统中发挥着重要作用。鱼类溶菌酶的研究有助于控制由病原体引起的鱼类感染。本综述回顾了鱼类溶菌酶的最新研究进展,包括其分类、结构特征、生物学功能和机制、组织分布以及重组蛋白的特性,这将有助于我们系统地了解鱼类溶菌酶,并促进其在食品和农业领域的应用。