McCutcheon N B, Guile M N, McCormick R
Physiol Behav. 1986;37(3):435-40. doi: 10.1016/0031-9384(86)90202-7.
The major purpose of Experiment 1 was to see if electrical stimulation of the brain in an area that supports self-stimulation can act during stress to attenuate the severity of gastric lesions produced by six hours of tailshock and restraint. It was found that rats receiving electrical stimulation of the medial forebrain bundle-posterior lateral hypothalamus had significantly less gastric pathology than control subjects not receiving stimulation. Further experiments sought to examine characteristics of the stimulation that would account for this finding. Experiments 2 and 3 studied signal and analgesic properties, respectively, of the brain stimulation, but did not find evidence for their involvement in the effect.
实验1的主要目的是探究，在支持自我刺激的脑区进行电刺激，能否在应激状态下减轻6小时尾部电击和束缚所导致的胃部损伤的严重程度。研究发现，接受内侧前脑束-下丘脑后外侧区电刺激的大鼠，其胃部病变程度明显低于未接受刺激的对照组。后续实验试图探究能解释这一结果的刺激特性。实验2和实验3分别研究了脑刺激的信号特性和镇痛特性，但均未发现它们与该效应有关的证据。
