Sorva R, Heiskanen O
Acta Neurochir (Wien). 1986;81(3-4):85-9. doi: 10.1007/BF01401226.
We report on 123 patients with craniopharyngioma diagnosed in Finland from 1951 to 1982. 45 patients were under 16 years of age at the time of diagnosis and 78 over 16 years. The age-distribution had peaks at 11-20 years and at 41-50 years. 115 patients were operated on; operation was radical in 67 cases (58%). Surgical mortality was 13%. The number of radical operations increased and surgical mortality decreased after 1970. Recurrence developed in 26 patients (21%), 11 after a radical and 15 after a non-radical operation. Recurrence-free survival, 10-year survival and life expectancy were best after radical operation. We consider that radical operation is the best treatment. For patients with a non-radical operation or with recurrence modern radiotherapy gives long-lasting relief.
我们报告了1951年至1982年在芬兰诊断出的123例颅咽管瘤患者。45例患者在诊断时年龄小于16岁,78例患者年龄大于16岁。年龄分布在11至20岁和41至50岁出现高峰。115例患者接受了手术;67例(58%)手术为根治性手术。手术死亡率为13%。1970年后根治性手术的数量增加,手术死亡率下降。26例患者(21%)出现复发,11例在根治性手术后复发,15例在非根治性手术后复发。根治性手术后无复发生存率、10年生存率和预期寿命最佳。我们认为根治性手术是最佳治疗方法。对于接受非根治性手术或复发的患者,现代放射治疗可带来持久缓解。