Taylor M B, Grounds R M, Mulrooney P D, Morgan M
Anaesthesia. 1986 Aug;41(8):816-20. doi: 10.1111/j.1365-2044.1986.tb13123.x.
The ventilatory effects of induction of anaesthesia with either propofol 2.5 mg/kg or thiopentone 4.0 mg/kg have been observed in patients premedicated with either atropine alone or papaveretum and hyoscine. Induction of anaesthesia with propofol was accompanied by a greater degree of ventilatory depression which was of longer duration than following thiopentone. The effect was accentuated by the opioid premedication.
在仅用阿托品或用吗啡和东莨菪碱进行术前用药的患者中，观察了分别用2.5mg/kg丙泊酚或4.0mg/kg硫喷妥钠诱导麻醉时的通气效应。丙泊酚诱导麻醉时伴有更严重的通气抑制，且持续时间比硫喷妥钠诱导后更长。阿片类药物术前用药会加重这种效应。
