Suppr超能文献

维生素C在新型冠状病毒肺炎治疗中的保护作用:综述

The protective role of vitamin C in the management of COVID-19: A Review.

作者信息

Uddin Mohammad Sarowar, Millat Md Shalahuddin, Baral Prodip Kumar, Ferdous Mahmuda, Uddin Md Giash, Sarwar Md Shahid, Islam Mohammad Safiqul

机构信息

Department of Pharmacy, Noakhali Science & Technology University, Noakhali, 3814, Bangladesh.

Department of Pharmacy, University of Chittagong, Chittagong, 4331, Bangladesh.

出版信息

J Egypt Public Health Assoc. 2021 Dec 11;96(1):33. doi: 10.1186/s42506-021-00095-w.

Abstract

BACKGROUND

The outbreak of coronavirus infectious disease-2019 (COVID-19) is globally deemed a significant threat to human life. Researchers are searching for prevention strategies, mitigation interventions, and potential therapeutics that may reduce the infection's severity. One such means that is highly being talked in online and in social media is vitamin C.

MAIN TEXT

Vitamin C is a robust antioxidant that boosts the immune system of the human body. It helps in normal neutrophil function, scavenging of oxidative species, regeneration of vitamin E, modulation of signaling pathways, activation of pro-inflammatory transcription factors, activation of the signaling cascade, regulation of inflammatory mediators, and phagocytosis and increases neutrophil motility to the site of infection. All of these immunological functions are required for the prevention of COVID-19 infection.

CONCLUSION

Considering the role of vitamin C, it would be imperative to administrate vitamin C for the management of severe COVID-19. However, there is no specific clinical data available to confirm the use of vitamin C in the current pandemic.

摘要

背景

2019年冠状病毒病(COVID-19)的爆发在全球范围内被视为对人类生命的重大威胁。研究人员正在寻找可能降低感染严重程度的预防策略、缓解干预措施和潜在治疗方法。维生素C就是在网络和社交媒体上被广泛讨论的一种方法。

正文

维生素C是一种强大的抗氧化剂,可增强人体免疫系统。它有助于正常的中性粒细胞功能、清除氧化物质、维生素E的再生、信号通路的调节、促炎转录因子的激活、信号级联的激活、炎症介质的调节以及吞噬作用,并增加中性粒细胞向感染部位的移动性。所有这些免疫功能都是预防COVID-19感染所必需的。

结论

考虑到维生素C的作用,对于重症COVID-19的治疗,给予维生素C势在必行。然而,目前尚无具体临床数据证实维生素C在当前疫情中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8746/8665912/faee70a708de/42506_2021_95_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验