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15 例 COVID-19 患者连续发生两次腹泻:病毒性腹泻后发生抗生素相关腹泻。

Two consecutive attacks of diarrhea in 15 COVID-19 patients: An antibiotic-associated one following the viral one.

机构信息

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow, Russian Federation; Scientific Community for Clinical Study of the Human Microbiome Research, Moscow, Russian Federation.

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow, Russian Federation.

出版信息

Rev Gastroenterol Mex (Engl Ed). 2022 Jan-Mar;87(1):59-62. doi: 10.1016/j.rgmxen.2021.06.008. Epub 2021 Dec 3.

DOI:10.1016/j.rgmxen.2021.06.008
PMID:34896030
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8639441/
Abstract

Of the 971 patients admitted to our Clinic with suspected COVID-19, 15 (1.5%) presented with two consecutive attacks of diarrhea. One of those patients (a 47-year-old woman) required admission to the intensive care unit and mechanical ventilation. She died on the 11th day of hospitalization (18th day of illness). The first attack of diarrhea in those patients occurred on the 6th (4th-7th) day of disease and lasted 3 (3-5) days. The second attack of diarrhea developed 11 (8-12) days after the initial onset of diarrhea. Despite the existing trend, the difference in the duration of the diarrhea and the maximum number of bowel movements per day between the first and second attacks was not statistically significant (p = 0.130; p = 0.328). There was no significant difference between the patients with a double attack of diarrhea and those with no diarrhea, regarding the results of the complete blood count, biochemical blood tests, and inflammation biomarkers.

摘要

在因疑似 COVID-19 而入住我院的 971 例患者中,有 15 例(1.5%)出现了两次连续的腹泻发作。其中一名患者(一名 47 岁女性)需要入住重症监护病房并接受机械通气。她于住院第 11 天(发病第 18 天)死亡。这些患者的第一次腹泻发作发生在疾病的第 6 天(第 4-7 天),持续了 3 天(3-5 天)。第二次腹泻发作发生在首次腹泻发作后 11 天(8-12 天)。尽管存在这种趋势,但第一次和第二次腹泻发作之间的腹泻持续时间和每天排便次数的差异没有统计学意义(p=0.130;p=0.328)。在两次腹泻发作的患者和没有腹泻的患者之间,血常规、生化血液检查和炎症生物标志物的结果没有显著差异。

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