School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Food Chem. 2022 Apr 16;374:131720. doi: 10.1016/j.foodchem.2021.131720. Epub 2021 Dec 4.
A magnetic molecularly imprinted polymer based on deep eutectic solvent was synthesized for specific identification and quantification of vanillin. FeO@SiO-CC and deep eutectic solvent were applied as the carrier of magnetic material and functional monomer, respectively. According to composition and morphology characterizations and adsorption kinetics, the imprinted polymer had excellent advantages on adsorption capacity and identification specificity for vanillin compared with non-imprinted polymer, while its reusability still remained stable. According to the high-performance liquid chromatography, the detection method based on imprinted polymer produced satisfactory analytical results. The limit of quantification was 0.2 μg·mL. The mean spiked recoveries for vanillin ranged from 91.2% to 100.2% with intra- and inter-day precision were both less than 7.2%. Compared to traditional extraction methods, this method presented best adsorption and extraction performances. In summary, the method could be further applied to the specific separation and quantification of vanillin in infant complementary food.
基于深共晶溶剂的磁性分子印迹聚合物被合成用于香草醛的特异性识别和定量。FeO@SiO-CC 和深共晶溶剂分别作为磁性材料和功能单体的载体。根据组成和形态特征以及吸附动力学，与非印迹聚合物相比，印迹聚合物在吸附容量和对香草醛的识别特异性方面具有优异的优势，而其可重复使用性仍然稳定。根据高效液相色谱法，基于印迹聚合物的检测方法产生了令人满意的分析结果。定量限为 0.2μg·mL。香草醛的平均加标回收率在 91.2%至 100.2%之间，日内和日间精密度均小于 7.2%。与传统的提取方法相比，该方法表现出最佳的吸附和提取性能。总之，该方法可以进一步应用于婴幼儿补充食品中香草醛的特异性分离和定量。
