Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China.
Chem Commun (Camb). 2022 Jan 4;58(3):411-414. doi: 10.1039/d1cc05865g.
An efficient iodine-mediated electrochemical C(sp)-H cyclization was developed under mild conditions. A variety of functionalized quinazolinone-fused N-heterocycles can be obtained with good to excellent yields by virtue of this method. The reaction features a broad substrate scope and scalability, and is metal-free and chemical oxidant-free.
一种高效的碘介导的电化学 C(sp 3 )-H 环化反应在温和条件下被开发出来。通过这种方法，可以以良好到优秀的收率得到多种功能化的喹唑啉酮并合的 N-杂环。该反应具有广泛的底物范围和可扩展性，并且无金属和化学氧化剂。
