Gettler Ján, Markovič Martin, Koóš Peter, Gracza Tibor
Department of Organic Chemistry, Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology, Radlinského 9, SK-812 37 Bratislava, Slovakia.
Molecules. 2024 Jul 26;29(15):3522. doi: 10.3390/molecules29153522.
This digest review summarises the most recent progress in the study on luotonins A, B and E. The literature covered in this overview spans from January 2012 to April 2024 and presents synthetic methodologies for the assembly of the quinolinopyrrolo-quinazoline scaffold, the structural motifs present in luotonins A, B, and E, and the evaluation of the biological activities of their derivatives and structural analogues.
本综述总结了鲁托宁A、B和E研究的最新进展。本综述涵盖的文献时间跨度从2012年1月至2024年4月,介绍了喹啉并吡咯并喹唑啉支架(鲁托宁A、B和E中存在的结构基序)的合成方法,以及其衍生物和结构类似物的生物活性评估。