Korovljev Darinka, Todorovic Nikola, Stajer Valdemar, Ostojic Sergej M
Applied Bioenergetics Lab, Faculty of Sport and Physical Education, University of Novi Sad, Novi Sad, Serbia.
Department of Nutrition and Public Health, University of Agder, Kristiansand, Norway.
Nutr Metab Insights. 2021 Dec 5;14:11786388211059368. doi: 10.1177/11786388211059368. eCollection 2021.
Several small-scale trials indicate a positive correlation between dietary creatine intake and fat-free mass in the pediatric population; whether this connection occurs at the population-wide level remains currently unknown. The main purpose of this cross-sectional study was to calculate the amount of creatine consumed through a regular diet among U.S. boys and girls aged 8 to 19 years, and investigate the link between creatine consumption and dual-energy X-ray absorptiometry (DXA)-derived body composition indices in this population. Data were obtained from the National Health and Nutrition Examination Survey 2017-2018 round, with dietary information and whole-body DXA body composition measures extracted for respondents aged 8 to 19 years (1273 participants, 649 boys and 624 girls). Individual values for total grams of creatine consumed per day for each participant were computed using the average amount of creatine (3.88 g/kg) across all creatine-containing foods. The primary exposure was the mean daily intake of creatine; the primary and secondary outcomes comprised lean mass excluding bone mineral content (BMC), and bone mineral density, BMC, lean mass including BMC, fat mass, and percent body fat, respectively. The average intake of creatine across the sample was 0.65 ± 0.72 g/day (95% CI, from 0.61 to 0.69). Creatine positively correlated with lean mass (excluding BMC) and BMC across the whole sample ( = .18 and .20, respectively; < .001); a significant negative correlation was found between creatine intake and percent body fat ( = -.09; = .001). The higher intake of creatine was associated with higher lean mass in girls and higher BMC in boys, while taking more creatine corresponded to less body fat for both genders ( < .05). Our findings indicate a significant correlation between dietary creatine and DXA-derived body composition biomarkers in a nationally representative cohort of U.S. youth. These results justify further research of creatine's role in modifying body morphology in the pediatric population, taking into account the age and sex specific traits.
几项小规模试验表明，儿童群体中膳食肌酸摄入量与去脂体重之间存在正相关；这种关联在整个人口中是否存在目前尚不清楚。这项横断面研究的主要目的是计算美国8至19岁男孩和女孩通过常规饮食摄入的肌酸量，并调查该人群中肌酸摄入量与双能X线吸收法（DXA）得出的身体成分指数之间的联系。数据来自2017 - 2018年全国健康与营养检查调查，提取了8至19岁受访者（1273名参与者，649名男孩和624名女孩）的饮食信息和全身DXA身体成分测量数据。使用所有含肌酸食物中的平均肌酸量（3.88 g/kg）计算每个参与者每天消耗的肌酸总克数的个体值。主要暴露因素是肌酸的每日平均摄入量；主要和次要结局分别包括排除骨矿物质含量（BMC）的瘦体重、骨矿物质密度、BMC、包括BMC的瘦体重、脂肪量和体脂百分比。样本中肌酸的平均摄入量为0.65±0.72 g/天（95% CI，0.61至0.69）。在整个样本中，肌酸与瘦体重（不包括BMC）和BMC呈正相关（分别为r = 0.18和0.20；P < 0.001）；发现肌酸摄入量与体脂百分比之间存在显著负相关（r = -0.09；P = 0.001）。较高的肌酸摄入量与女孩较高的瘦体重和男孩较高的BMC相关，而摄入更多肌酸对应于男女两性较低的体脂（P < 0.05）。我们的研究结果表明，在美国青少年具有全国代表性的队列中，膳食肌酸与DXA得出的身体成分生物标志物之间存在显著相关性。考虑到年龄和性别特异性特征，这些结果证明有必要进一步研究肌酸在改变儿童身体形态方面的作用。
