Gastroenterology Department, Braga Hospital.
Life and Health Sciences Research Institute ICVS, School of Medicine, University of Minho, Braga, Portugal.
Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e961-e969. doi: 10.1097/MEG.0000000000002330.
The aim of this study was to validate the IBD-Disk in a Portuguese cohort according to the COnsensus-based Standards for the selection of the health Measurement INstruments (COSMIN) recommendations.
After translation of the original IBD-Disk to Portuguese, a group of IBD patients was invited to complete the IBD-Disk at baseline (T0), after 1-4 weeks (T1) and after more than 3 months (T2), from July 2020 to February 2021. At T0 and T2, the patients also completed the IBD Disability Index. We evaluated reliability (internal consistency, test-retest, interrater reliability and measurement error), construct validity, responsiveness, interpretability of IBD-Disk, sociodemographic and clinical factors associated with IBD-Disk.
At T0, 154 patients (107 - Crohn's disease; 46 - ulcerative colitis) completed the IBD-Disk; 1 - IBD-unclassified). At T1 and T2, 64 and 114 patients repeated the questionnaire, respectively. Factor analysis confirmed the unidimensionality of the scale and reduced the final version to 10 items. Internal consistency was excellent with a Cronbach's α of 0.916. The intraclass correlation coefficient was 0.95 for test-retest (T0 and T1). To evaluate construct validity, the IBD-Disk was compared with the IBD Disability Index and Manitoba IBD Index with a significative positive correlation (r = 0.850 and r = 0.459, respectively; P < 0.001 for both). IBD-Disk scores ranged from 0 to 93 with a mean of 38.18 ± 25.39. Female sex, professional inactivity, longer IBD duration and clinical activity were associated with significantly higher IBD-Disk scores.
The Portuguese version of IBD-Disk is a reliable and valid tool to assess disability in Portuguese IBD patients.
本研究旨在根据共识基础的健康测量工具选择标准（COSMIN）建议，对葡萄牙队列中的 IBD-Disk 进行验证。
在将原始 IBD-Disk 翻译成葡萄牙语后，一组 IBD 患者被邀请在 2020 年 7 月至 2021 年 2 月期间完成 IBD-Disk 的基线（T0）、1-4 周后（T1）和 3 个月后（T2）的测量。在 T0 和 T2，患者还完成了 IBD 残疾指数的测量。我们评估了 IBD-Disk 的可靠性（内部一致性、重测信度、评分者间信度和测量误差）、结构效度、反应度、可解释性，以及与 IBD-Disk 相关的社会人口学和临床因素。
在 T0，154 名患者（107 名克罗恩病患者；46 名溃疡性结肠炎患者）完成了 IBD-Disk 的测量；1 名 IBD 未分类患者）。在 T1 和 T2，分别有 64 名和 114 名患者重复了问卷。因子分析证实了量表的单维性，并将最终版本简化为 10 个项目。内部一致性非常好，克朗巴赫的α值为 0.916。T0 和 T1 的组内相关系数为 0.95。为了评估结构效度，将 IBD-Disk 与 IBD 残疾指数和马尼托巴 IBD 指数进行比较，发现与两者均有显著正相关（r=0.850 和 r=0.459，均为 P<0.001）。IBD-Disk 的评分范围为 0 到 93，平均值为 38.18±25.39。女性、非职业活动、较长的 IBD 病程和临床活动与 IBD-Disk 的评分显著升高相关。
葡萄牙语版的 IBD-Disk 是一种可靠和有效的工具，可以评估葡萄牙语 IBD 患者的残疾程度。
