Singh Arshdeep, Gupta Yogesh Kumar, Dhaliwal Ashvin Singh, Kahlon Bhavjeet Kaur, Bansal Vasu, Mahajan Ramit, Mehta Varun, Singh Dharmatma, Kaur Ramandeep, Bansal Namita, Midha Vandana, Sood Ajit
Department of Gastroenterology, Dayanand Medical College, Ludhiana, India.
Department of Internal Medicine, Dayanand Medical College, Ludhiana, India.
Intest Res. 2023 Jul;21(3):375-384. doi: 10.5217/ir.2022.00037. Epub 2022 Oct 18.
BACKGROUND/AIMS: The inflammatory bowel disease (IBD)-disk is a validated, visual, 10-item, self-administered questionnaire used to evaluate IBD-related disability. The present study aimed to evaluate IBD-disk in assessment of IBD daily life burden and its relation with disease activity.
A cross-sectional study was conducted between June 2021 and December 2021. Patients with IBD were asked to complete the IBD-disk and a visual analogue scale of IBD daily-life burden (scored from 0-10, score >5 indicative of high burden). The internal consistency of IBD-disk, correlation with IBD daily life burden and disease activity (assessed by partial Mayo score and Harvey Bradshaw Index in patients with ulcerative colitis [UC] and Crohn's disease [CD], respectively) and diagnostic performance of IBD-disk to detect high burden were analyzed.
Out of the 546 patients (mean age 40.33±13.74 years, 282 [51.6%] males) who completed the IBD-disk, 464 (84.98%) had UC and the remaining (n=82, 15.02%) had CD. A total of 311 patients (291 UC and 20 CD; 56.95%) had active disease. The mean IBD-disk total score and IBD daily life burden were 18.39±15.23 and 2.45±2.02, respectively. The IBD-disk total score correlated strongly with the IBD daily life burden (ρ=0.94, P<0.001), moderately with partial Mayo score (ρ=0.50) and weakly with Harvey Bradshaw Index (ρ=0.34). The IBD-disk total score >30 predicted high IBD daily-life burden.
The IBD-disk accurately predicts the daily life burden and parallels disease activity in patients with IBD and can be applied in clinical practice. (Intest Res, Published online).
背景/目的：炎症性肠病（IBD）-量表是一种经过验证的、直观的、包含10个项目的自填式问卷，用于评估IBD相关残疾情况。本研究旨在评估IBD-量表在评估IBD日常生活负担及其与疾病活动度关系方面的作用。
于2021年6月至2021年12月进行了一项横断面研究。IBD患者被要求完成IBD-量表以及一份IBD日常生活负担视觉模拟量表（评分范围为0至10分，得分>5分表示负担较重）。分析了IBD-量表的内部一致性、与IBD日常生活负担及疾病活动度的相关性（分别通过部分梅奥评分评估溃疡性结肠炎[UC]患者以及通过哈维·布拉德肖指数评估克罗恩病[CD]患者的疾病活动度），以及IBD-量表检测高负担的诊断性能。
在完成IBD-量表的546例患者（平均年龄40.33±13.74岁，男性282例[51.6%]）中，464例（84.98%）患有UC，其余82例（15.02%）患有CD。共有311例患者（291例UC患者和20例CD患者；56.95%）患有活动性疾病。IBD-量表总分及IBD日常生活负担的平均值分别为18.39±15.23和2.45±2.02。IBD-量表总分与IBD日常生活负担密切相关（ρ=0.94，P<0.001），与部分梅奥评分中度相关（ρ=0.50），与哈维·布拉德肖指数轻度相关（ρ=0.34）。IBD-量表总分>30分可预测IBD日常生活负担较重。
IBD-量表能够准确预测IBD患者的日常生活负担，并与疾病活动度平行，可应用于临床实践。（《肠道研究》，在线发表）
