Daga Pawan, Shah Ira
Department of Paediatrics, B J Wadia Hospital for Children, Mumbai, Maharashtra, India.
Pediatric HIV Clinic, Department of Pediatric Infectious Diseases, B J Wadia Hospital for Children, Mumbai, Maharashtra, India.
Indian J Sex Transm Dis AIDS. 2021 Jul-Dec;42(2):175-176. doi: 10.4103/ijstd.IJSTD_27_19. Epub 2021 Nov 9.
HIV infection can lead to venous thrombosis due to protein C deficiency, protein S deficiency, or antiphospholipid syndrome. Most patients present with deep vein thrombosis or pulmonary embolism. We report a 10-years-old HIV-infected girl who presented with life-threatening hematemesis. Computed tomography scan of the abdomen and angiography showed thrombosis of the portal vein, superior mesenteric vein, and splenic vein. She was advised antiretroviral therapy and prothrombotic workup, however, she took discharge against medical advice.
HIV感染可因蛋白C缺乏、蛋白S缺乏或抗磷脂综合征导致静脉血栓形成。大多数患者表现为深静脉血栓形成或肺栓塞。我们报告一名10岁的HIV感染女孩,她出现了危及生命的呕血。腹部计算机断层扫描和血管造影显示门静脉、肠系膜上静脉和脾静脉血栓形成。她被建议接受抗逆转录病毒治疗和血栓前状态检查,然而,她不听从医嘱自行出院。