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一例转移性鳞状细胞癌所致肺肿瘤栓塞的尸检病例

An Autopsy Case of Pulmonary Tumor Emboli Due to Metastatic Squamous Cell Carcinoma.

作者信息

Alsaggaf Mohammed, Bawa Amandeep S, Khosla Rahul

机构信息

Pulmonary and Critical Care Medicine, George Washington University Hospital, Washington DC, USA.

Pulmonary and Critical Care Medicine, Veterans Affairs Medical Center, Washington DC, USA.

出版信息

Cureus. 2021 Nov 12;13(11):e19506. doi: 10.7759/cureus.19506. eCollection 2021 Nov.

DOI:10.7759/cureus.19506
PMID:34912643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8664405/
Abstract

A 74-year-old man with chronic obstructive pulmonary disease on home oxygen and coronary artery disease was transferred from an outside facility to obtain an inguinal lymph node biopsy to rule out malignancy. He underwent an uncomplicated procedure and was discharged the same day. While waiting for transportation, he had sudden-onset dyspnea and collapsed. After resuscitation, patient had return of spontaneous circulation and was admitted but was provided comfort care and soon expired. Autopsy showed metastatic squamous cell carcinoma with multiple bilateral tumor emboli. Pulmonary tumor embolism is a rare cause of dyspnea in cancer population. Most of the cases are diagnosed with autopsy after sudden death; however, few cases have been reported antemortem. Tumor embolism is rare and difficult to diagnose without an autopsy with a poor outcome.

摘要

一名74岁男性,患有慢性阻塞性肺疾病,在家中吸氧,同时患有冠状动脉疾病,从外地医疗机构转来进行腹股沟淋巴结活检以排除恶性肿瘤。他接受了一次无并发症的手术,并于当天出院。在等待转运时,他突然出现呼吸困难并晕倒。复苏后,患者恢复自主循环并入院,但接受了舒适护理,不久后死亡。尸检显示为转移性鳞状细胞癌,伴有多个双侧肿瘤栓子。肺肿瘤栓塞是癌症患者呼吸困难的罕见原因。大多数病例在猝死后通过尸检诊断;然而,生前报告的病例很少。肿瘤栓塞罕见,若无尸检则难以诊断,预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/280078bd24ad/cureus-0013-00000019506-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/aecc3198a007/cureus-0013-00000019506-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/d3d2ed757e39/cureus-0013-00000019506-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/79c67ab49b2e/cureus-0013-00000019506-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/280078bd24ad/cureus-0013-00000019506-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/aecc3198a007/cureus-0013-00000019506-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/d3d2ed757e39/cureus-0013-00000019506-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/79c67ab49b2e/cureus-0013-00000019506-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1211/8664405/280078bd24ad/cureus-0013-00000019506-i04.jpg

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本文引用的文献

1
Massive tumor embolism in the abdominal aorta from pulmonary squamous cell carcinoma: Case report and review of the literature.巨块型肿瘤栓子致腹主动脉转移:来自肺鳞癌的病例报告及文献复习。
Pathol Int. 2017 Sep;67(9):467-471. doi: 10.1111/pin.12554. Epub 2017 Jun 27.
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