Paschalis C, Jenner F A, Lee C R
J R Soc Med. 1978 May;71(5):343-52. doi: 10.1177/014107687807100507.
Clinical studies of the effects of rubidium ions on the course of manic-depressive illness are reported. It seems that rubidium tends to increase the length of manic phases and possibly reduces the extremes of mood. Rubidium did not seem to produce any severe side effects in the dose administered, but it has a long biological half-life and caution is still required. Some details of the CSF, RBC, saliva and plasma and urine kinetics are also reported.
本文报道了铷离子对躁郁症病程影响的临床研究。铷似乎会延长躁狂期的时长,并可能减轻情绪的极端波动。在所使用的剂量下,铷似乎未产生任何严重的副作用,但它具有较长的生物半衰期,仍需谨慎使用。文中还报告了脑脊液、红细胞、唾液、血浆及尿液动力学的一些细节。