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沙特阿拉伯东部地区胃食管反流病的患病率及相关危险因素

Prevalence of Gastroesophageal Reflux Disease and Associated Risk Factors in the Eastern Region, Saudi Arabia.

作者信息

Al Ghadeer Hussain A, Alabbad Zahra E, AlShaikh Salwa B, Ahmed Shaheen U, Bu-Khamseen Ali A, Alhashem Ali T, Alhamrani Alaa H, AlGhadeer Mohammed R, Alibrahim Dhiyaa A, Alkishi Bassil M

机构信息

Paediatrics, Maternity and Children Hospital, AlAhsa, SAU.

Internal Medicine, King Faisal University, AlAhsa, SAU.

出版信息

Cureus. 2021 Nov 15;13(11):e19599. doi: 10.7759/cureus.19599. eCollection 2021 Nov.

Abstract

Background Gastroesophageal reflux disease (GERD) is a common upper gastrointestinal disorder characterized by heartburn and acid regurgitation. A higher incidence is found in Arab countries. Untreated GERD has a negative impact on individuals that interfere with daily activities and impaired quality of life. This study aims to estimate the prevalence of GERD and associated risk factors in the Eastern region, Saudi Arabia. Material & Methodology A descriptive cross-sectional study was carried out among 1517 healthy participants from the Eastern province of Saudi Arabia from May to August 2021. The sample was randomly collected through a structured self-administered questionnaire. The questionnaire was composed of questions related to sociodemographic and lifestyle characteristics as risk factors for GERD. The existence of GERD was assessed by using GERD Questionnaire (GerdQ) for diagnosing GERD, when the score is 8 or more. Results A total of 1517 participants were included in the study: 58.8% male, 41.2% female; 9% of whom were pregnant. The age of participants ranged from 18 to 58 with a mean age of 27.5 ± 11.4 years old. The existence of GERD was 20.6% among the total participants, in which their GerdQ scores were 3-7 (68.9%), 8-10 (22.1%), and 8-11 (8.5%). The higher risk groups of having GERD were pregnant women, smoker, being male, regular usage of analgesia, soft drinks, and having a family history of GERD. Conclusion This study showed the prevalence of GERD among the general population of the Eastern region, Saudi Arabia was 20.6%. Several sociodemographic and lifestyle characteristics were associated with the disease. Further studies are needed to explore the role of psychological factors in developing GERD.

摘要

背景 胃食管反流病(GERD)是一种常见的上消化道疾病,其特征为烧心和反酸。在阿拉伯国家,该病发病率较高。未经治疗的胃食管反流病会对个体产生负面影响,干扰日常活动并损害生活质量。本研究旨在评估沙特阿拉伯东部地区胃食管反流病的患病率及相关危险因素。

材料与方法 2021年5月至8月,对沙特阿拉伯东部省份的1517名健康参与者进行了一项描述性横断面研究。通过结构化的自填问卷随机收集样本。问卷包含与社会人口统计学和生活方式特征相关的问题,这些特征作为胃食管反流病的危险因素。使用胃食管反流病问卷(GerdQ)评估胃食管反流病的存在情况,当分数为8分及以上时可诊断为胃食管反流病。

结果 本研究共纳入1517名参与者:男性占58.8%,女性占41.2%;其中9%为孕妇。参与者年龄在18至58岁之间,平均年龄为27.5±11.4岁。在所有参与者中,胃食管反流病的患病率为20.6%,其中GerdQ评分为3 - 7分的占68.9%,8 - 10分的占22.1%,8 - 11分的占8.5%。患胃食管反流病风险较高的群体包括孕妇、吸烟者、男性、经常使用镇痛药、软饮料以及有胃食管反流病家族史的人。

结论 本研究表明,沙特阿拉伯东部地区普通人群中胃食管反流病的患病率为20.6%。一些社会人口统计学和生活方式特征与该病有关。需要进一步研究以探讨心理因素在胃食管反流病发病中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a47/8671076/d224385236bf/cureus-0013-00000019599-i01.jpg

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