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烧心和反流对普通人群个体健康的影响:巴西全国性调查。

IMPACT OF HEARTBURN AND REGURGITATION ON INDIVIDUALS' WELL-BEING IN THE GENERAL POPULATION: A BRAZILIAN NATIONAL SURVEY.

机构信息

Universidade de São Paulo, Faculdade de Medicina, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Universidade do Estado do Rio de Janeiro, Faculdade de Medicina, Departamento de Gastroenterologia, Rio de Janeiro, RJ, Brasil.

出版信息

Arq Gastroenterol. 2021 Jan-Mar;58(1):5-9. doi: 10.1590/S0004-2803.202100000-03.

DOI:10.1590/S0004-2803.202100000-03
PMID:33909797
Abstract

BACKGROUND

Heartburn and acid regurgitation are typical symptoms usually associated with gastroesophageal reflux disease (GERD). GERD is one of the gastrointestinal diagnosis with higher prevalence worldwide, significantly impairing patients' quality of life.

OBJECTIVE

The objective of this study was to analyze the impact of GERD-related symptoms in the Brazilian urban population.

METHODS

National telephone survey with community-dwelling Brazilian individuals. Self-reported prevalence and frequency of symptoms (heartburn / regurgitation) were assessed. Individuals rated the impact of symptoms in their general well-being using a numeric scale from 1 to 10 (1 = no impact; 10 = very intense, preventing the person to eat and perform daily routine activities). Descriptive and bivariate statistical analyses were performed.

RESULTS

The final sample was comprised of 1,773 subjects, 935 (52.7%) females, an average of 40 years old. The prevalence of heartburn and regurgitation in the past 6 months was 26.2% (n=466) and 11.0% (n=196), respectively. Women presented higher prevalence (heartburn n=266, 28.5% and regurgitation n=119, 12.7%) than men (n=200, 23.1% and n=78, 8.9%, respectively) (P<0.05). Heartburn in the past week was reported by 175 individuals (9.8%), while regurgitation episodes by 67 (3.8%). Absence of impact of the symptom in the overall well-being was observed for 82 subjects (17.6%) with heartburn and 18 individuals (9.2%) with regurgitation. Very intense impact was reported by 46 subjects (9.8%) with heartburn and 41 (20.9%) with regurgitation. Women's well-being was more affected than men's (mean score 5.45 vs 4.71, P<0.05).

CONCLUSION

Heartburn and regurgitation were frequent symptoms, women with higher prevalence. These symptoms led to a substantial impact on individuals' well-being, women being more affected.

摘要

背景

烧心和反酸是胃食管反流病(GERD)的典型症状。GERD 是全球患病率较高的胃肠道疾病之一,显著降低了患者的生活质量。

目的

本研究旨在分析 GERD 相关症状对巴西城市人群的影响。

方法

采用全国电话调查的方法,对居住在社区的巴西个体进行调查。评估症状(烧心/反流)的自报告患病率和频率。个体使用 1 到 10 的数字量表(1 = 无影响;10 = 非常剧烈,使人无法进食和进行日常活动)来评价症状对整体健康状况的影响。进行描述性和双变量统计分析。

结果

最终样本由 1773 名受试者组成,其中 935 名(52.7%)为女性,平均年龄 40 岁。过去 6 个月烧心和反流的患病率分别为 26.2%(n=466)和 11.0%(n=196)。女性的患病率高于男性(烧心 n=266,28.5%和 n=119,12.7%,vs 男性 n=200,23.1%和 n=78,8.9%,P<0.05)。过去一周有 175 名(9.8%)个体出现烧心,67 名(3.8%)出现反流症状。82 名(17.6%)烧心患者和 18 名(9.2%)反流患者报告症状对整体健康状况无影响。46 名(9.8%)烧心患者和 41 名(20.9%)反流患者报告症状对健康状况影响非常剧烈。女性的健康状况受影响比男性更严重(平均评分 5.45 比 4.71,P<0.05)。

结论

烧心和反流是常见症状,女性的患病率更高。这些症状对个体的健康状况产生了重大影响,女性受影响更严重。

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