Shuguang Hospital Health Examination Center Affiliated with Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Department of Biostatistics and Epidemiology, College of Public Health, University of South Florida, Tampa, FL 33612, USA.
J Diabetes Res. 2021 Dec 10;2021:3243135. doi: 10.1155/2021/3243135. eCollection 2021.
Brachial-ankle pulse wave velocity (baPWV) is a noninvasive clinical test that provides quantification for the stiffness of both the aorta and peripheral arteries by measuring the brachial and tibial arterial wave velocities. The temporal pattern of baPWV values during aging was investigated in this paper. A gradual increase in baPWV with respect to age was observed, suggesting an increase in the stiffness of arterial vessels as age increases. The baPWV value, defined as the absolute value of the difference between bilateral baPWV, also showed a positive correlation with aging. Many underlying physiological conditions such as hyperlipidemia, hypertension, diabetes, and hyperglycemia have previously been shown to elevate baPWV and contribute to the decline of arterial function. The effect of factors including biological sex, blood pressure, and blood glucose levels on the baPWV temporal pattern were also investigated. Between the ages of 18 and 50, men in the study had significantly higher baPWV readings than females of comparable age on average. However, after the age of 50, mean baPWV values increased at a greater rate in females than in males. In addition, blood pressure and blood glucose were shown to be associated with baPWV values. The results will improve existing prediction models for future cardiovascular episodes induced by arterial hardening in different age groups.
肱踝脉搏波速度（baPWV）是一种非侵入性的临床检测方法，通过测量肱动脉和胫动脉的波速来定量评估主动脉和外周动脉的僵硬程度。本文研究了 baPWV 值随年龄的变化规律。随着年龄的增长，baPWV 值逐渐增加，表明动脉血管的僵硬程度随年龄的增长而增加。baPWV 值定义为双侧 baPWV 差值的绝对值，也与年龄呈正相关。先前的研究表明，许多潜在的生理条件，如高血脂、高血压、糖尿病和高血糖，都会升高 baPWV，导致动脉功能下降。本文还研究了生物性别、血压和血糖水平等因素对 baPWV 时间变化的影响。在 18 至 50 岁之间，研究中的男性的 baPWV 读数平均高于同年龄的女性。然而，在 50 岁之后，女性的平均 baPWV 值增加速度比男性更快。此外，血压和血糖与 baPWV 值相关。这些结果将改善现有的预测模型，以便在不同年龄组中预测由动脉僵硬引起的未来心血管事件。
