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新冠病毒的新变种,印度全基因组策略面临的新挑战:公共卫生视角

Newer variants of COVID-19, newer challenges of whole-genome strategy in India: A public health perspective.

作者信息

Laskar Ananya Ray, Garg Suneela, Kumar Raman, Yadav Kartikey, Gopal K Madan

机构信息

Department Community Medicine, Lady Hardinge Medical College and Former Deputy Director Epid, NCDC, New Delhi, India.

Maulana Azad Medical College, FMS & Advisor ICMRTask Force DBT, New Delhi, India.

出版信息

J Family Med Prim Care. 2021 Oct;10(10):3540-3543. doi: 10.4103/jfmpc.jfmpc_417_21. Epub 2021 Nov 5.

DOI:10.4103/jfmpc.jfmpc_417_21
PMID:34934643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8653467/
Abstract

The sudden upsurge in the newly emerging COVID-19 variants acted as a catalyst for India to scale up the viral Genomic surveillance in order to understand the nature and trends of the newer variants of concern and strengthen public health interventions across the country. The Government of India has proposed the Indian SARS-CoV-2 Genomics Consortium to expand the whole-genome sequencing (WGS) of this virus. However, in a vast country like India introduction and implementation of any new strategies amidst the already existing barriers due to COVID-19 will be a herculean task. This paper talks about how the primary care physicians can play a vital role in successful implementation of the above strategy in addition to the surveillance systems in India.

摘要

新出现的新冠病毒变异株的突然激增,促使印度加大了病毒基因组监测力度,以了解新出现的关注变异株的性质和趋势,并加强全国的公共卫生干预措施。印度政府提议成立印度SARS-CoV-2基因组联盟,以扩大对这种病毒的全基因组测序(WGS)。然而,在像印度这样幅员辽阔的国家,在因新冠疫情已经存在的障碍中引入和实施任何新战略都将是一项艰巨的任务。本文探讨了除印度的监测系统外,基层医疗医生如何在成功实施上述战略中发挥至关重要的作用。

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本文引用的文献

1
New variant of SARS-CoV-2 in UK causes surge of COVID-19.英国出现的新冠病毒新变种导致新冠肺炎病例激增。
Lancet Respir Med. 2021 Feb;9(2):e20-e21. doi: 10.1016/S2213-2600(21)00005-9. Epub 2021 Jan 5.
2
Genomic sequencing effort for SARS-CoV-2 by country during the pandemic.各国在大流行期间针对 SARS-CoV-2 进行的基因组测序工作。
Int J Infect Dis. 2021 Feb;103:305-307. doi: 10.1016/j.ijid.2020.12.034. Epub 2020 Dec 14.
3
Genomic analysis of SARS-CoV-2 strains among Indians returning from Italy, Iran & China, & Italian tourists in India.对从意大利、伊朗和中国返回的印度人以及在印度的意大利游客中新冠病毒2型毒株的基因组分析。
Indian J Med Res. 2020;151(2 & 3):255-260. doi: 10.4103/ijmr.IJMR_1058_20.
4
Full-genome sequences of the first two SARS-CoV-2 viruses from India.印度最早发现的两种 SARS-CoV-2 病毒的全基因组序列。
Indian J Med Res. 2020;151(2 & 3):200-209. doi: 10.4103/ijmr.IJMR_663_20.
5
Epidemiologic data and pathogen genome sequences: a powerful synergy for public health.流行病学数据与病原体基因组序列:公共卫生领域的强大协同作用。
Genome Biol. 2014 Nov 18;15(11):538. doi: 10.1186/s13059-014-0538-4.