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2-脱氧-D-葡萄糖(2-DG)在新冠病毒疾病中的作用:一个潜在的变革因素。

Role of 2-Deoxy-D-Glucose (2-DG) in COVID-19 disease: A potential game-changer.

作者信息

Sahu Kamal K, Kumar Raman

机构信息

Division of Hematology and Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States.

President, Academy of Family Physicians of India, New Delhi, India.

出版信息

J Family Med Prim Care. 2021 Oct;10(10):3548-3552. doi: 10.4103/jfmpc.jfmpc_1338_21. Epub 2021 Nov 5.

Abstract

Virus infections can cause tissue damage in many ways. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a cause of the current COVID-19 pandemic, has been extensively studied so far to investigate its pathophysiology and evaluate its impact on the metabolic system of human cells. This has given a lead to study the role of 2-deoxy-D-glucose (2DG) against COVID-19 disease. We hereby would like to briefly discuss the concept and rationale behind the use of 2DG COVID-19.

摘要

病毒感染可通过多种方式导致组织损伤。严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是当前新冠疫情的病原体,迄今为止,人们对其进行了广泛研究,以探究其病理生理学并评估其对人类细胞代谢系统的影响。这为研究2-脱氧-D-葡萄糖(2DG)对抗新冠疾病的作用提供了线索。在此,我们想简要讨论使用2DG治疗新冠的概念和基本原理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0add/8653447/e6ec5a716ee0/JFMPC-10-3548-g001.jpg

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