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香港华人非霍奇金淋巴瘤的免疫组织学亚型

Immunohistological subtypes of non-Hodgkin's lymphoma in Hong Kong Chinese.

作者信息

Ho F C, Loke S L, Hui P K, Todd D

出版信息

Pathology. 1986 Oct;18(4):426-30. doi: 10.3109/00313028609087563.

DOI:10.3109/00313028609087563
PMID:3493471
Abstract

One hundred and four unselected cases of non-Hodgkin's lymphoma (NHL) in adult Chinese patients in Hong Kong were typed, using monoclonal and conventional antibodies, by immunoenzymatic labelling methods on cryostat sections or cell smears. The total included 69 cases (66%) of B-cell and 26 (25%) of T-cell tumours. The diffuse large cell (centroblastic or immunoblastic) types formed the largest proportion (44.9%) of B lymphomas. Of 26 cases of T-cell lymphoma 25 were of peripheral type; of these 25, the most frequent subtype (42.3%) was the immunoblastic lymphadenopathy-like lesion. Although there were 9 pleomorphic T-cell lymphomas, none of the patients presented with the adult T-cell leukemia/lymphoma syndrome. The incidence of T-cell lymphomas in our population is not markedly higher than that of western countries, but there are some interesting differences in the types of T-cell lymphomas that are commonly seen.

摘要

利用单克隆抗体和传统抗体,通过免疫酶标记法,对香港成年中国患者的104例未经挑选的非霍奇金淋巴瘤(NHL)病例在冷冻切片或细胞涂片上进行分型。其中包括69例(66%)B细胞肿瘤和26例(25%)T细胞肿瘤。弥漫性大细胞(中心母细胞性或免疫母细胞性)类型在B淋巴瘤中占比最大(44.9%)。在26例T细胞淋巴瘤中,25例为外周型;在这25例中,最常见的亚型(42.3%)是免疫母细胞淋巴结病样病变。虽然有9例多形性T细胞淋巴瘤,但无一例患者表现为成人T细胞白血病/淋巴瘤综合征。我们人群中T细胞淋巴瘤的发病率并不明显高于西方国家,但在常见的T细胞淋巴瘤类型上存在一些有趣的差异。

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1
Immunohistological subtypes of non-Hodgkin's lymphoma in Hong Kong Chinese.香港华人非霍奇金淋巴瘤的免疫组织学亚型
Pathology. 1986 Oct;18(4):426-30. doi: 10.3109/00313028609087563.
2
Immunophenotypic analysis of non-Hodgkin's lymphomas in Chinese. A study of 75 cases in Hong Kong.中国非霍奇金淋巴瘤的免疫表型分析。香港75例病例研究。
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An immunocytochemical study of T-cell lymphomas using monoclonal and polyclonal antibodies effective in routinely fixed wax embedded tissues.一项使用对常规固定石蜡包埋组织有效的单克隆和多克隆抗体对T细胞淋巴瘤进行的免疫细胞化学研究。
Histopathology. 1986 Dec;10(12):1243-60. doi: 10.1111/j.1365-2559.1986.tb02568.x.
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Immunopathology of non-Hodgkin lymphomas.非霍奇金淋巴瘤的免疫病理学
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Low grade malignant non-Hodgkin's lymphomas and peripheral pleomorphic T-cell lymphomas in childhood--a BFM study group report.儿童低度恶性非霍奇金淋巴瘤和外周多形性T细胞淋巴瘤——一项BFM研究组报告
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