Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.
Vascular Disease Institute of Central South University, Changsha, China.
Interact Cardiovasc Thorac Surg. 2022 Feb 21;34(3):446-452. doi: 10.1093/icvts/ivab359.
Aortic arch type is a readily recognizable and obtainable morphological feature of the aorta that does not require complex measurements. The goal of this study was to evaluate whether aortic arch type is a comparable and alternative morphological parameter for predicting acute type B aortic dissection (aTBAD) by comparing the prognostic value of the aortic arch type with that of other morphological parameters such as aortic length, angulation and tortuosity index.
The patients with aTBAD (n = 216) were matched 1:1 with a control group (n = 263) by propensity score matching. The morphological data of the ascending aorta and the aortic arch, which included diameter, length, angulation and tortuosity index, were collected on a three-dimensional aortic model using 3mensio Vascular software. The aortic arch type was identified by the vertical distance from the origin of the brachiocephalic trunk to the top of the arch. The binary logistic regression models were analysed to determine the independent geometric variables related to the aTBAD. The nonparametric approach was performed to assess whether there were statistical differences between the area under the receiver operating characteristic curves (AUC) of the models.
After propensity score matching, 151 matched pairs of patients were selected. The diameters at the sinotubular junction and the mid-ascending aorta, the ascending aorta length and the ascending aorta angulation in the aTBAD group were significantly greater than those of the controls. Compared with the control group, the diameters at the proximal aortic arch, mid-aortic arch and distal aortic arch, the angulation and the tortuosity index of the aortic arch were significantly greater in the aTBAD group. The proportion of the type III arch in the patients with aTBAD is higher than that of the type I arch and the type II arch (χ2 = 70.187; P < 0.001). Binary logistic regression analysis showed that the diameter at the mid-aortic arch, the ascending aorta length, the aortic arch angulation and the tortuosity index were independently related to the aTBAD with an AUC value of 0.887. Another binary logistic regression analysis indicated that the diameter at the mid-aortic arch and the aortic arch type were independent correlative variables associated with the aTBAD with an AUC of 0.874. No significant difference was observed in the prognostic value of receiver operating characteristic curves between the 2 models (P = 0.716).
The type III arch, which has the characteristics of aortic elongation, incremental angulation and tortuosity index, is a comparable and alternative identifier for patients at high risk for aTBAD.
主动脉弓类型是主动脉易于识别和获取的形态特征,不需要复杂的测量。本研究的目的是通过比较主动脉弓类型与其他形态参数(如主动脉长度、角度和扭曲指数)的预测价值,评估主动脉弓类型是否可作为急性 B 型主动脉夹层(aTBAD)的一种可比且替代的形态学参数。
通过倾向性评分匹配,将 216 例 aTBAD 患者与对照组(n=263)1:1 匹配。使用 3mensio 血管软件,在三维主动脉模型上采集升主动脉和主动脉弓的形态学数据,包括直径、长度、角度和扭曲指数。主动脉弓类型通过头臂干起始处到弓顶的垂直距离来确定。采用二元逻辑回归模型分析与 aTBAD 相关的独立几何变量。采用非参数方法评估模型的接收者操作特征曲线(ROC)下面积(AUC)之间是否存在统计学差异。
经倾向性评分匹配后,选择了 151 对匹配的患者。aTBAD 组的窦管交界处和升主动脉中段直径、升主动脉长度和升主动脉角度明显大于对照组。与对照组相比,aTBAD 组近端主动脉弓、中段主动脉弓和远端主动脉弓直径、角度和扭曲指数明显增大。aTBAD 患者的 III 型弓比例高于 I 型弓和 II 型弓(χ2=70.187;P<0.001)。二元逻辑回归分析显示,主动脉弓中段直径、升主动脉长度、主动脉弓角度和扭曲指数与 aTBAD 独立相关,AUC 值为 0.887。另一项二元逻辑回归分析表明,主动脉弓中段直径和主动脉弓类型是与 aTBAD 相关的独立相关变量,AUC 为 0.874。两个模型的 ROC 曲线的预测价值无显著差异(P=0.716)。
具有主动脉伸长、递增角度和扭曲指数特征的 III 型弓是 aTBAD 高危患者的一种可比且替代的识别标志。