Logan M R, Duggan J E, Levack I D, Spence A A
Br J Anaesth. 1987 Feb;59(2):179-83. doi: 10.1093/bja/59.2.179.
A single i.v. bolus dose of propofol 3 mg kg-1 was compared with methohexitone 2 mg kg-1 as the sole anaesthetic agent for simple dental extraction in outpatients. Induction of anaesthesia was smoother with propofol, with a lower incidence of excitatory phenomena. Pain on injection was a common complication of both drugs and related to the site of injection. The Leeds Psychomotor Tester was used to assess psychomotor performance during the recovery. Rate of recovery from anaesthesia was similar with both agents, and there was little residual impairment of psychomotor function 40 min after induction.
将丙泊酚3 mg·kg⁻¹单次静脉推注剂量与甲己炔巴比妥2 mg·kg⁻¹作为门诊患者简单拔牙的唯一麻醉剂进行比较。丙泊酚诱导麻醉更平稳,兴奋现象发生率更低。注射疼痛是两种药物的常见并发症,且与注射部位有关。使用利兹精神运动测试仪评估恢复期间的精神运动表现。两种药物的麻醉恢复率相似,诱导后40分钟精神运动功能几乎没有残留损害。