Department of Disinfection and Supply, Weifang People's Hospital, Weifang, China.
Comput Math Methods Med. 2021 Dec 13;2021:3171547. doi: 10.1155/2021/3171547. eCollection 2021.
Patients' clinical antibiotic treatment of deep II degree burns usually fails to achieve the ideal effect; in order to avoid the late result in pigmentation, scarring, and even limb dysfunction, it also needs to deal effectively with burn wounds.
The purpose of this study is to evaluate nanosilver dressing in treating deep II degree burn wound infection in patients with clinical studies.
106 burn patients were classified into the Sulfadiazine Silver Cream (SSC) group ( = 53) and the Nanosilver Burn Dressing (NSBD) group ( = 53). Both of them received basic wound treatment, and wound healing time and pigmentation fading away time of all patients were recorded. And the wound healing rate of the patients was calculated. Serum levels of tumor necrosis factor alpha (TNF-) and interleukin-1beta (IL-1) were detected pre- and posttreatment.
After basic treatment for all patients, Sulfadiazine Silver Cream was used in the SSC group, and Nanosilver Burn Dressing was used in the NSBD group. It was observed that after treatment, compared with the SSC group, there was significant efficiency; wound healing rate, healing time, and pigmentation fading away time were shortened in the NSBD group, and IL-1 levels were decreased, and the positive rate of bacterial culture was decreased (all < 0.05).
Nanosilver Burn Dressing in treating deep II degree burns can effectively reduce the wound infection and promote wound healing. The curative effect was distinct, which was worthy of popularization and application.
患者对深度 II 度烧伤的临床抗生素治疗通常无法达到理想效果；为了避免色素沉着、瘢痕形成甚至肢体功能障碍等晚期后果，还需要有效处理烧伤创面。
本研究旨在评估纳米银敷料治疗深度 II 度烧伤创面感染的临床疗效。
将 106 例烧伤患者分为磺胺嘧啶银乳膏（SSC）组（n = 53）和纳米银烧伤敷料（NSBD）组（n = 53）。两组患者均接受基础创面处理，记录所有患者的创面愈合时间和色素消退时间，并计算患者的创面愈合率。检测治疗前后患者血清肿瘤坏死因子-α（TNF-α）和白细胞介素-1β（IL-1）水平。
所有患者经基础治疗后，SSC 组外用磺胺嘧啶银乳膏，NSBD 组外用纳米银烧伤敷料。治疗后观察到，与 SSC 组相比，NSBD 组的治疗效果显著；NSBD 组的创面愈合率、愈合时间和色素消退时间均缩短，IL-1 水平降低，细菌培养阳性率降低（均 P < 0.05）。
纳米银烧伤敷料治疗深度 II 度烧伤可有效降低创面感染，促进创面愈合。疗效显著，值得推广应用。
