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钛合金表面羟基磷灰石层的仿生沉积

Biomimetic Deposition of Hydroxyapatite Layer on Titanium Alloys.

作者信息

Baltatu Madalina Simona, Sandu Andrei Victor, Nabialek Marcin, Vizureanu Petrica, Ciobanu Gabriela

机构信息

Faculty of Materials Science and Engineering, Gheorghe Asachi Technical University of Iasi, 41 D. Mangeron Street, 700050 Iasi, Romania.

Romanian Inventors Forum, 3 Sf. P. Movila St, 700089 Iasi, Romania.

出版信息

Micromachines (Basel). 2021 Nov 25;12(12):1447. doi: 10.3390/mi12121447.

Abstract

Over the last decade, researchers have been concerned with improving metallic biomaterials with proper and suitable properties for the human body. Ti-based alloys are widely used in the medical field for their good mechanical properties, corrosion resistance and biocompatibility. The TiMoZrTa system (TMZT) evidenced adequate mechanical properties, was closer to the human bone, and had a good biocompatibility. In order to highlight the osseointegration of the implants, a layer of hydroxyapatite (HA) was deposited using a biomimetic method, which simulates the natural growth of the bone. The coatings were examined by scanning electron microscopy (SEM), X-ray diffraction (XRD), micro indentation tests and contact angle. The data obtained show that the layer deposited on TiMoZrTa (TMZT) support is hydroxyapatite. Modifying the surface of titanium alloys represents a viable solution for increasing the osseointegration of materials used as implants. The studied coatings demonstrate a positive potential for use as dental and orthopedic implants.

摘要

在过去十年中,研究人员一直致力于改进具有适合人体特性的金属生物材料。钛基合金因其良好的机械性能、耐腐蚀性和生物相容性而广泛应用于医学领域。TiMoZrTa体系(TMZT)表现出足够的机械性能,与人体骨骼更为接近,并且具有良好的生物相容性。为了突出植入物的骨整合,采用仿生方法沉积了一层羟基磷灰石(HA),该方法模拟了骨骼的自然生长。通过扫描电子显微镜(SEM)、X射线衍射(XRD)、微压痕试验和接触角对涂层进行了检测。获得的数据表明,沉积在TiMoZrTa(TMZT)载体上的层是羟基磷灰石。对钛合金表面进行改性是提高用作植入物材料的骨整合的可行解决方案。所研究的涂层显示出用作牙科和矫形植入物的积极潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e3/8704239/894c6a6bcf42/micromachines-12-01447-g001.jpg

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