Shimamura Yuko, Inagaki Ryo, Oike Minami, Dong Beibei, Gong Wan, Masuda Shuichi
School of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.
Foods. 2021 Nov 24;10(12):2905. doi: 10.3390/foods10122905.
Glycidyl fatty acid esters (GEs), which are the main pollutant in processed oils, are potential mutagens or carcinogens. 3-Monochloropropane-1,2-diol fatty acid esters (3-MCPDEs) are also well-known food processing contaminants. 3-MCPDEs are believed to be a precursor to GEs in foodstuffs. In vivo, lipase breaks down the phosphate ester of GEs and 3-MCPDEs to produce glycidol and 3-MCPD, respectively, which are genotoxic carcinogens. Thus, it is important to determine human exposure to GEs and 3-MCPDEs through foodstuffs. There are only reports on the amount of GE and 3-MCPDE in cooking oils and cooked foods. The content in multiple types of foods that are actually on the market was not clarified. In this study, 48 commercially prepared foods were analyzed to identify other sources of exposure to GE and 3-MCPDE. All of them contained relatively high amounts of GEs and 3-MCPDEs. The correlation between GEs and 3-MCPDEs in individual foods was examined. There was a correlation between the amounts of GEs and 3-MCPDEs in the food products ( = 0.422, < 0.005). This is the first report on the content in multiple types of commercially prepared foods that are actually on the market was clarified.
缩水甘油脂肪酸酯(GEs)是加工油中的主要污染物,具有潜在的致突变性或致癌性。3-单氯丙二醇脂肪酸酯(3-MCPDEs)也是著名的食品加工污染物。3-MCPDEs被认为是食品中GEs的前体。在体内,脂肪酶分别分解GEs和3-MCPDEs的磷酸酯,产生具有基因毒性的致癌物缩水甘油和3-MCPD。因此,确定人类通过食品接触GEs和3-MCPDEs的情况很重要。目前仅有关于食用油和熟食品中GE和3-MCPDE含量的报道。市场上实际多种食品中的含量尚不清楚。在本研究中,对48种商业制备食品进行了分析,以确定接触GEs和3-MCPDEs的其他来源。所有这些食品都含有相对较高含量的GEs和3-MCPDEs。研究了单个食品中GEs和3-MCPDEs之间的相关性。食品中GEs和3-MCPDEs的含量之间存在相关性( = 0.422,< 0.005)。这是首次对市场上实际多种商业制备食品中的含量进行明确报道。