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乳制品乳酸菌及其在营养学中的潜在作用:食物-肠道-健康轴

Dairy Lactic Acid Bacteria and Their Potential Function in Dietetics: The Food-Gut-Health Axis.

作者信息

Ağagündüz Duygu, Yılmaz Birsen, Şahin Teslime Özge, Güneşliol Bartu Eren, Ayten Şerife, Russo Pasquale, Spano Giuseppe, Rocha João Miguel, Bartkiene Elena, Özogul Fatih

机构信息

Department of Nutrition and Dietetics, Gazi University, Emek, Ankara 06490, Turkey.

Department of Nutrition and Dietetics, Cukurova University, Sarıcam, Adana 01380, Turkey.

出版信息

Foods. 2021 Dec 14;10(12):3099. doi: 10.3390/foods10123099.

Abstract

Fermented dairy products are the good source of different species of live lactic acid bacteria (LAB), which are beneficial microbes well characterized for their health-promoting potential. Traditionally, dietary intake of fermented dairy foods has been related to different health-promoting benefits including antimicrobial activity and modulation of the immune system, among others. In recent years, emerging evidence suggests a contribution of dairy LAB in the prophylaxis and therapy of non-communicable diseases. Live bacterial cells or their metabolites can directly impact physiological responses and/or act as signalling molecules mediating more complex communications. This review provides up-to-date knowledge on the interactions between LAB isolated from dairy products (dairy LAB) and human health by discussing the concept of the food-gut-health axis. In particular, some bioactivities and probiotic potentials of dairy LAB have been provided on their involvement in the gut-brain axis and non-communicable diseases mainly focusing on their potential in the treatment of obesity, cardiovascular diseases, diabetes mellitus, inflammatory bowel diseases, and cancer.

摘要

发酵乳制品是不同种类活性乳酸菌(LAB)的良好来源,这些有益微生物因其促进健康的潜力而得到充分表征。传统上,食用发酵乳制品与多种促进健康的益处相关,包括抗菌活性和免疫系统调节等。近年来,新出现的证据表明乳制品乳酸菌在非传染性疾病的预防和治疗中发挥作用。活细菌细胞或其代谢产物可直接影响生理反应和/或作为介导更复杂通讯的信号分子。本综述通过讨论食物-肠道-健康轴的概念,提供了关于从乳制品中分离出的乳酸菌(乳制品乳酸菌)与人类健康之间相互作用的最新知识。特别是,已经阐述了乳制品乳酸菌在肠道-脑轴和非传染性疾病中的一些生物活性和益生菌潜力,主要聚焦于它们在治疗肥胖症、心血管疾病、糖尿病、炎症性肠病和癌症方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd56/8701325/6c1977f52168/foods-10-03099-g001.jpg

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