新西兰南北部多发性硬化症的发病情况。
Occurrence of multiple sclerosis in the north and south of New Zealand.
作者信息
Skegg D C, Corwin P A, Craven R S, Malloch J A, Pollock M
出版信息
J Neurol Neurosurg Psychiatry. 1987 Feb;50(2):134-9. doi: 10.1136/jnnp.50.2.134.
Abstract
An impression that multiple sclerosis is commoner in southern parts of New Zealand than in the north has never been tested rigorously. Identical methods were used to determine the prevalence and incidence of multiple sclerosis in two regions: the Waikato (in the North Island) and Otago and Southland (in the South Island). No cases were found in Maoris, while the expected number was 11.7. The prevalence rate of multiple sclerosis (excluding possible cases) in non-Maoris was 24 per 100,000 in the northern region and 69 per 100,000 in the south. The incidence rate was also more than twice as high in the southern region. These findings are considered in relation to genetic and environmental hypotheses about the aetiology of multiple sclerosis.
摘要
有一种观点认为，新西兰南部多发性硬化症的发病率高于北部，但这一观点从未得到过严格验证。我们采用相同的方法来确定两个地区多发性硬化症的患病率和发病率：怀卡托地区（位于北岛）以及奥塔哥和南岛地区（位于南岛）。在毛利人群中未发现病例，而预期病例数为11.7例。非毛利人群中多发性硬化症（不包括疑似病例）的患病率在北部地区为每10万人中有24例，在南部地区为每10万人中有69例。南部地区的发病率也是北部地区的两倍多。我们结合关于多发性硬化症病因的遗传和环境假说对这些发现进行了考量。
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