Petersen T
Acta Neurol Scand. 1987 Jan;75(1):52-5. doi: 10.1111/j.1600-0404.1987.tb07888.x.
Several forms of treatment of lower urinary tract functional disorders have been attempted in children with myelomeningocele (MMC). Intravesical electrical stimulation was attempted in 10 patients. Urinary control was achieved in one and in the remaining 9 either the bladder was resistant to stimulation or the children discontinued the treatment due to loss of interest. A combined anticholinergic and calcium blocking agent, terodiline, was tested in 8: symptoms improved in 4, but bladder compliance was unchanged. Clean intermittent catheterization, either alone or in combination with medication, seems to be the most beneficial treatment.
针对患有脊髓脊膜膨出(MMC)的儿童,已经尝试了几种治疗下尿路功能障碍的方法。对10名患者尝试了膀胱内电刺激。1名患者实现了控尿,其余9名患者中,要么膀胱对刺激有抵抗,要么儿童因兴趣丧失而停止治疗。在8名患者中测试了一种抗胆碱能和钙阻滞剂的组合药物——特罗地林:4名患者症状改善,但膀胱顺应性未改变。清洁间歇性导尿,单独使用或与药物联合使用,似乎是最有益的治疗方法。