Petersen T, Jakobsen J
Department of Neurology, University Hospital of Aarhus, Denmark.
J Neurol Neurosurg Psychiatry. 1987 Oct;50(10):1331-6. doi: 10.1136/jnnp.50.10.1331.
In 25 neurological patients with detrusor hyperreflexia terodiline reduced the number of total micturitions during daytime. Bladder capacity was increased and amplitude of the bladder contractions was reduced. An increase in residual urine was also observed. Mild anticholinergic side-effects were measured on pupillary motility and on heart rate variation. It is concluded that terodiline is a useful alternative in treatment of patients with detrusor hyperreflexia.
在25例患有逼尿肌反射亢进的神经科患者中,特罗地林减少了白天总的排尿次数。膀胱容量增加,膀胱收缩幅度减小。还观察到残余尿量增加。在瞳孔运动和心率变化方面检测到轻微的抗胆碱能副作用。得出的结论是,特罗地林是治疗逼尿肌反射亢进患者的一种有用的替代药物。