Vintzileos A M, Campbell W A, Nochimson D J, Weinbaum P J
Am J Obstet Gynecol. 1987 May;156(5):1235-8. doi: 10.1016/0002-9378(87)90153-0.
A retrospective study of 298 patients with preterm premature rupture of the membranes managed expectantly during a 3-year period investigated the association between preterm premature rupture of the membranes and abruptio placentae. Expectant management was associated with the development of abruptio placentae in 19 of these 298 patients (6.3%). The prevalence of abruptio placentae in the entire population during the same 3-year period was 2.7%, whereas in patients without preterm premature rupture of the membranes it was 2%. None of the patients developed clinical or laboratory evidence of disseminated intravascular coagulation and no infection (maternal or neonatal) was noted among the patients who had abruptio placentae. Patients with preterm premature rupture of the membranes and severe oligohydramnios (largest pocket less than 1 cm) seem to be at particular risk for developing this complication. These data suggest that abruptio placentae should be considered as one of the possible risks of expectant management in preterm premature rupture of the membranes.
一项对298例胎膜早破患者进行的回顾性研究，这些患者在3年期间接受了期待治疗，该研究调查了胎膜早破与胎盘早剥之间的关联。在这298例患者中，有19例（6.3%）的期待治疗与胎盘早剥的发生有关。在同一3年期间，整个人口中胎盘早剥的患病率为2.7%，而在没有胎膜早破的患者中为2%。所有患者均未出现弥散性血管内凝血的临床或实验室证据，且发生胎盘早剥的患者中未发现感染（母体或新生儿）。胎膜早破且羊水过少（最大羊水池小于1厘米）的患者似乎特别容易发生这种并发症。这些数据表明，胎盘早剥应被视为胎膜早破期待治疗的可能风险之一。
