Nelson D M, Stempel L E, Zuspan F P
J Reprod Med. 1986 Apr;31(4):249-53.
Nine patients with prolonged, preterm premature rupture of the membranes (PROM) had associated abruptio placentae confirmed at delivery. Antepartum vaginal bleeding during the course of expectant management was the most common feature in the clinical course of the patients who developed abruptio placentae. Other clinical and laboratory findings suggesting the diagnosis were not present consistently. Retrospective analysis of all patients with prolonged, preterm PROM led to an estimated risk of 4% for the development of abruptio placentae during the course of expectant management of such patients. This risk estimate is three to eight times greater than that for the development of abruptio placentae in pregnancy generally. A high index of suspicion for abruptio placentae is appropriate when patients with prolonged, preterm PROM develop vaginal bleeding or any other suggestive clinical signs or symptoms of abruptio placentae during the course of expectant management.
9例胎膜早破时间延长的早产患者在分娩时确诊合并胎盘早剥。期待治疗过程中的产前阴道出血是发生胎盘早剥患者临床过程中最常见的特征。其他提示诊断的临床和实验室检查结果并非始终存在。对所有胎膜早破时间延长的早产患者进行回顾性分析发现，在此类患者的期待治疗过程中，发生胎盘早剥的估计风险为4%。这一风险估计比一般妊娠中发生胎盘早剥的风险高3至8倍。当胎膜早破时间延长的早产患者在期待治疗过程中出现阴道出血或任何其他提示胎盘早剥的临床体征或症状时，应高度怀疑胎盘早剥。
