鸡蛋摄入与中国人群代谢综合征的关系：一项横断面研究。
Association between egg consumption and metabolic syndrome in Chinese population: a cross-sectional study.
机构信息
Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.
Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
出版信息
BMJ Open. 2021 Dec 24;11(12):e050317. doi: 10.1136/bmjopen-2021-050317.
OBJECTIVES
Metabolic syndrome (MS) comprises a constellation of symptoms that include abdominal obesity, hypertension, hyperglycaemia and dyslipidaemia. Dietary intake is a crucial environmental risk factor for MS, but the exact association between MS and egg consumption, which accounts for more than half of the daily total cholesterol intake in Chinese population, has not been previously studied. The aim of this study was to examine the correlation between dietary egg consumption and the prevalence of MS in the context of a large population.
DESIGN
A cross-sectional study.
SETTINGS
Our study was conducted in a health examination centre in China.
PARTICIPANTS
Participants who aged ≥40 years and received routine physical examinations were included for analyses.
MAIN OUTCOME MEASURES
MS was diagnosed in accordance with the clinical diagnosis criteria specified in the American Heart Association Guidelines. Egg consumption was assessed by a validated semi-quantitative food frequency questionnaire.
RESULTS
A total of 11 529 participants (46.2% women) were included in the present study. On the basis of multivariable logistic regression analysis, egg consumption was negatively associated with the prevalence of MS after adjusting for dietary energy intake (OR=0.84, 95% CI 0.76 to 0.93, p value for trend=0.001). The above findings did not change with further adjustment for other potential confounders: model 2 was further adjusted for age, body mass index and sex (based on model 1) and model 3 was further adjusted for education level, physical activity level, smoking status, alcohol use status, dietary fat intake, dietary fibre intake and nutritional supplementation (based on model 2). Consistent results were obtained from the analysis in the female subgroup but not in male subjects.
CONCLUSIONS
A higher level of egg consumption was associated with a lower prevalence of MS in our study participants, and particularly in female subjects.
目的
代谢综合征（MS）是一组症状的统称，包括腹部肥胖、高血压、高血糖和血脂异常。饮食摄入是 MS 的一个重要环境风险因素，但 MS 与鸡蛋摄入之间的确切关联，在中国人的日常总胆固醇摄入量中，鸡蛋占一半以上，尚未得到研究。本研究旨在探讨在大人群中饮食鸡蛋摄入与 MS 患病率之间的相关性。
设计
横断面研究。
地点
我们的研究在中国的一个健康检查中心进行。
参与者
≥40 岁并接受常规体检的参与者被纳入分析。
主要观察指标
MS 根据美国心脏协会指南中规定的临床诊断标准进行诊断。鸡蛋摄入量通过经过验证的半定量食物频率问卷进行评估。
结果
本研究共纳入 11529 名参与者（46.2%为女性）。基于多变量逻辑回归分析，在校正膳食能量摄入后，鸡蛋摄入量与 MS 的患病率呈负相关（OR=0.84，95%CI 0.76 至 0.93，趋势检验 p 值=0.001）。进一步调整其他潜在混杂因素后，上述发现没有改变：模型 2进一步调整了年龄、体重指数和性别（基于模型 1），模型 3进一步调整了教育水平、体力活动水平、吸烟状况、饮酒状况、膳食脂肪摄入量、膳食纤维摄入量和营养补充剂（基于模型 2）。在女性亚组的分析中得到了一致的结果，但在男性中没有得到一致的结果。
结论
在本研究参与者中，较高的鸡蛋摄入量与 MS 的患病率较低相关，特别是在女性中。
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