Department of Clinical Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Sci Rep. 2023 Feb 16;13(1):2778. doi: 10.1038/s41598-023-30018-y.
Existing evidence examining the relation between egg consumption and metabolic health of overweight/obese adolescents is scarce. We examined the association between egg consumption and metabolic status in Iranian overweight/obese adolescents. Using multistage cluster random sampling approach, overweight/obese adolescents (n = 203) with ages from 12 to 18 years old were selected for the present cross-sectional study. A validated 147-item food frequency questionnaire was adopted to determine usual dietary intakes. Blood pressure and anthropometric data and were assessed, and levels of lipid profile, insulin, and glucose were measured by collecting fasting blood samples. Participants were classified into metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO) based on two methods of International Diabetes Federation (IDF) and the combination of IDF with Homeostasis Model Assessment Insulin Resistance (HOMA-IR). In total, 67 (33.0%) and 79 (38.9%) adolescents were classified as MUO based on IDF/HOMA and IDF definitions, respectively. Considering IDF criteria, the highest intake of egg was related to decreased chance of MUO, in crude (OR 0.22; 95% CI 0.10-0.48) and maximally-adjusted model (OR 0.25; 95% CI 0.10-0.59). Considering IDF/HOMA-IR criteria, similar results were obtained (crude model: OR 0.24; 95% CI 0.11-0.52; fully-adjusted model: OR 0.28; 95% CI 0.11-0.69). Stratified analyses found stronger relation among boys (vs. girls) and overweight (vs. obese) individuals. In conclusion, higher egg consumption was negatively related to decreased chance of being MUO in overweight/obese adolescents, especially in boys and overweight individuals, regardless of MUO definitions. Prospective studies are required to support our results.
现有的证据表明，鸡蛋摄入与超重/肥胖青少年代谢健康之间的关系尚不清楚。我们研究了伊朗超重/肥胖青少年中鸡蛋摄入与代谢状况之间的关系。采用多阶段聚类随机抽样方法，选择年龄在 12 至 18 岁之间的超重/肥胖青少年（n=203）进行本横断面研究。采用经过验证的 147 项食物频率问卷来确定习惯性饮食摄入量。评估血压和人体测量数据，并通过采集空腹血样来测量血脂谱、胰岛素和血糖水平。根据国际糖尿病联合会（IDF）的两种方法和 IDF 与稳态模型评估胰岛素抵抗（HOMA-IR）相结合的方法，将参与者分为代谢健康肥胖（MHO）或代谢不健康肥胖（MUO）。根据 IDF/HOMA 和 IDF 定义，共有 67（33.0%）和 79（38.9%）名青少年分别被归类为 MUO。考虑到 IDF 标准，鸡蛋摄入量最高与 MUO 机会降低有关，在未调整（OR 0.22；95%CI 0.10-0.48）和最大调整模型（OR 0.25；95%CI 0.10-0.59）中均如此。考虑到 IDF/HOMA-IR 标准，也得到了类似的结果（未调整模型：OR 0.24；95%CI 0.11-0.52；完全调整模型：OR 0.28；95%CI 0.11-0.69）。分层分析发现，在男孩（与女孩相比）和超重（与肥胖相比）个体中，这种关系更强。总之，在超重/肥胖青少年中，鸡蛋摄入较高与 MUO 机会降低呈负相关，无论 MUO 定义如何，这种关系在男孩和超重个体中更为明显。需要进行前瞻性研究来支持我们的结果。
