估算撒哈拉以南非洲男性商用车驾驶员高血压及其主要危险因素的负担：系统评价和荟萃分析。

Estimating the burden of hypertension and its significant risk factors among male commercial drivers in sub-Saharan Africa: A systematic review and meta-analysis.

机构信息

Department of Physiotherapy, Korle Bu Teaching Hospital, Accra, Ghana

Department of Epidemiology and Disease Control, University of Ghana, Legon, Ghana.

出版信息

BMJ Open. 2021 Dec 24;11(12):e053825. doi: 10.1136/bmjopen-2021-053825.

DOI:10.1136/bmjopen-2021-053825

PMID:34952880

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8712980/

Abstract

OBJECTIVE

The study was designed to assess the burden and significant risk factors among male commercial drivers in sub-Saharan Africa (SSA).

DESIGN

Systematic review and meta-analysis.

DATA SOURCES

Medline via PubMed, Google Scholar, Cochrane databases and were searched from January 2010 to December 2020.

ELIGIBILITY CRITERIA FOR SELECTING STUDIES

The authors included observational studies reporting on the burden and/or risk factors for hypertension among commercial drivers in SSA. Male adult population ≥18 years working as a commercial driver in SSA as well articles published in English.

DATA EXTRACTION AND SYNTHESIS

Two independent coauthors used a prepared data extraction form to extract data from the eligible published papers and assessed the risk of bias. DerSimonian and Laird random effects model was used to pool the burden of hypertension and significant risk factors among male commercial drivers in SSA. The presence of heterogeneity among studies was quantified by estimating variance using both Cochrane's Q statistics and the I statistics. A subgroup and sensitivity analyses were performed.

RESULTS

Overall, 14 articles met the inclusion criteria involving a total of 4285 male commercial drivers in SSA. The estimated pooled burden of hypertension among the male commercial drivers in SSA was 32% (95% CI 24% to 39%). The risk factors identified were age OR=1.10 (95% CI 1.06 to 1.15), overweight/obese OR=3.38 (95% CI 2.46 to 4.29), alcohol consumption OR=3.00 (95% CI 2.05 to 3.95) and duration of driving (≥5 years) OR=1.83 (95% CI 1.03 to 2.63). Funnel plot inspection and Egger's regression test of small effect (0.5838) showed no evidence of publication bias.

CONCLUSIONS

Our review showed that nearly one-third of male commercial drivers in SSA have hypertension. Reduction of modifiable risk factors such as overweight/obesity, alcohol consumption and long-term driving through multifaceted implementation strategies are recommended for prevention and control of hypertension among male commercial drivers in SSA.

TRIAL REGISTRATION NUMBER

CRD42021250910.

摘要

目的

本研究旨在评估撒哈拉以南非洲（SSA）男性商业司机的负担和显著危险因素。

设计

系统评价和荟萃分析。

数据来源

从 2010 年 1 月至 2020 年 12 月，通过 Medline（PubMed）、Google Scholar、Cochrane 数据库和进行检索。

入选研究的标准

作者纳入了报告 SSA 商业司机高血压负担和/或危险因素的观察性研究。年龄≥18 岁的成年男性，作为 SSA 的商业司机，以及以英文发表的文章。

数据提取和综合

两位独立的合著者使用准备好的数据提取表从合格的已发表论文中提取数据，并评估偏倚风险。采用 DerSimonian 和 Laird 随机效应模型来汇总 SSA 男性商业司机高血压的负担和显著危险因素。使用 Cochrane's Q 统计量和 I 统计量来估计方差，以量化研究之间的异质性。进行了亚组和敏感性分析。

结果

共有 14 篇文章符合纳入标准，共涉及 4285 名 SSA 男性商业司机。估计 SSA 男性商业司机高血压的总负担为 32%（95%CI 24%至 39%）。确定的危险因素包括年龄 OR=1.10（95%CI 1.06 至 1.15）、超重/肥胖 OR=3.38（95%CI 2.46 至 4.29）、饮酒 OR=3.00（95%CI 2.05 至 3.95）和驾驶时间（≥5 年）OR=1.83（95%CI 1.03 至 2.63）。漏斗图检查和 Egger 回归检验小效应（0.5838）表明不存在发表偏倚的证据。