Hong H, Zhang D D, Jiang H B, Shi H B, Tan S W, Gu W Z, Xu G Z
Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Dec 10;42(12):2100-2105. doi: 10.3760/cma.j.cn112338-20210811-00632.
To investigate the situation related to HIV infection and influencing factors of traceability efficiency among sex partners of HIV positive men who have sex with men (MSM). A cross-sectional survey was conducted to investigate the traceability among sex partners of HIV-positive MSM in Ningbo from 2018 to 2020. Limiting-antigen avidity enzyme immunoassay determined recent HIV infection. The classified data was evaluated by chi-square test, and factors of traceability efficiency were analyzed by multivariate logistic regression. A total of 374 newly confirmed HIV-positive MSM were recruited to participate in the HIV test in Ningbo from 2018 to 2020.HIV positive rate of sex partner was 15.7% (75/479,95%12.4%-18.9%). HIV positive rates of sex partner of recent HIV infection MSM was 31.8% (21/66,95%:20.3%-43.4%). The proportion of newly confirmed HIV-positive sex partners of recent HIV infection MSM (76.2%) was higher than that of long-term HIV infection MSM (48.1%). The difference was statistically significant (=0.028). Results from the multivariate logistic regression analysis showed that HIV traceability efficiency was higher in the following subpopulations as; HIV positive MSM who were 36-45 years old (compared with 18-25 years old, =3.973,95%:1.364-11.569), HIV active detection (compared with HIV passive detection, =1.896, 95%:1.083-3.319), recent HIV infection MSM (compared with long-term HIV infection MSM, =3.733, 95%:1.844-7.556). HIV positive rate among partners of HIV positive MSM was very high. The traceability efficiency, which was recent HIV infection MSM and HIV active detection, was high. It is suggested to strengthen the traceability and focus on the newly confirmed HIV-positive MSM in VCT clinics.
调查男男性行为者（MSM）中HIV阳性者性伴的HIV感染情况及溯源效率的影响因素。采用横断面调查方法，对2018年至2020年宁波市HIV阳性MSM的性伴进行溯源调查。采用限量抗原亲和力酶免疫法确定近期HIV感染情况。分类资料采用χ²检验进行评价，溯源效率的影响因素采用多因素logistic回归分析。2018年至2020年，宁波市共招募374例新确诊的HIV阳性MSM进行HIV检测。性伴HIV阳性率为15.7%（75/479，95%CI：12.4% - 18.9%）。近期HIV感染MSM的性伴HIV阳性率为31.8%（21/66，95%CI：20.3% - 43.4%）。近期HIV感染MSM新确诊的HIV阳性性伴比例（76.2%）高于长期HIV感染MSM（48.1%）。差异有统计学意义（P = 0.028）。多因素logistic回归分析结果显示，36 - 45岁的HIV阳性MSM（与18 - 25岁相比，OR = 3.973，95%CI：1.364 - 11.569）、HIV主动检测（与HIV被动检测相比，OR = 1.896，95%CI：1.083 - 3.319）、近期HIV感染MSM（与长期HIV感染MSM相比，OR = 3.733，95%CI：1.844 - 7.556）等亚人群的HIV溯源效率较高。HIV阳性MSM的性伴中HIV阳性率很高。近期HIV感染MSM和HIV主动检测的溯源效率较高。建议加强溯源工作，关注VCT门诊新确诊的HIV阳性MSM。
